臺灣博碩士論文加值系統

本文提出以單模光纖為基礎，將單模光纖彎曲後製作成彎曲型光纖感測器，再結合模具高溫燒製、自組裝奈米金感測層及靜電紡絲等製程技術，分別製作出能對溫度、生醫及濕度進行量測的光纖感測器。
本研究的第一部分是將單模光纖放入陶瓷模具中進行燒製，製作出一種可以量測高溫的光纖感測器，當此感測器在量測30 °C至1200 °C的溫度範圍時，皆可以得到相當線性的變化，波長靈敏度為-0.00915 nm/°C，傳輸損耗靈敏度為0.00865 dB/°C。
本研究的第二部分是在彎曲型光纖感測器上，以自組裝的方式在光纖感測器上塗覆奈米金生醫感測層，此感測器能接種胃泌素-17抗體(Anti-Gastrin)，並成功量測到胃泌素-17(Gastrin-17)，實驗結果顯示，以濃度4 ug/ml的抗體在量測濃度12.5 ug/ml的抗原時，可達到12.910 nm的波長變化量。
最後本研究的第三部分是在彎曲型光纖感測器上製作濕度感測層，本研究使用靜電紡絲的技術，將聚乙烯醇(Polyvinyl alcohol；PVA)高分子材料與石墨烯量子點(Graphene Quantum Dots；GQD)的混合物製作成奈米尺度的絲，並將絲纏繞在彎曲型光纖感測器上製作而成，此感測器能量測濕度，在30 %RH至80 %RH的溼度範圍內可以量測到濕度的變化，波長靈敏度為0.004 nm/%RH，傳輸損耗靈敏度為0.119 dB/%RH。

In this paper, we based on the single-mode fiber proposed a curved optical fiber sensor which is bend a single-mode fiber made to a curved optical fiber, combined with high temperature mould firing, self-assembling nano-gold sensing layer and electrostatic spinning technology to produce optical fiber sensors respectively for temperature, biomedical and humidity measurements.
In the first part of this study, a single-mode optical fiber was into a ceramic mould then be fired that be produce a high-temperature sensor. Over a temperature range of 30 °C to 1200 °C which has a good linear variation, the best wavelength sensitivity can reach of -0.00915 nm/°C and transmission loss sensitivity can reach of 0.00865 dB/°C .
In the second part of this study is based on curved optical fiber sensor, an self-assembled manner nano-gold bio-medical sensing layer was applied to a curved fiber optic sensor. The sensor is capable of inoculating Anti-Gastrin and has successfully measured Gastrin-17. The experimental results show that the wavelength variation can reach of 12.910 nm when used antibody concentration of 4 ug/ml for measuring antigen concentration of 12.5 ug/ml.
Finally, the third part of this study is manufacture of a humidity sensing layer on curved fiber optic sensor. An mixture of polyvinyl alcohol (PVA) polymer and graphene quantum dots (GQD) was made into nano-grade filaments using an electrostatic spinning technology, and the filaments were wound around a curved optical fiber sensor. This sensor can measuring humidity variations between humidity range of 30 %RH to 80%RH, which the best wavelength sensitivity can reach of 0.004 nm/%RH and transmission loss sensitivity can reach of 0.119 dB/%RH.

致謝
摘要
ABSTRACT
目錄
圖目錄
表目錄
第一章 序論
1.1 研究動機
1.2 文獻回顧
1.2.1 光纖溫度感測器文獻
1.2.2 光纖生醫感測器文獻
1.2.3 光纖濕度感測器文獻
第二章 基礎理論
2.1 光纖傳輸基本原理
2.2 彎曲型光纖基礎理論
第三章 研究方法與步驟
3.1 彎曲型光纖感測器製造方法
3.2 高溫感測彎曲型光纖感測器
3.2.1 高溫彎曲型光纖感測器製作方法
3.2.2 溫度量測實驗架構
3.3 自組裝生醫彎曲型光纖感測器
3.3.1 彎曲型光纖感測器自組裝生醫感測層製程
3.3.2 生醫量測實驗架構
3.4 濕度感測彎曲型光纖感測器
3.4.1 彎曲型光纖感測器披覆靜電紡絲製程
3.4.2 濕度量測實驗架構
第四章 實驗結果與討論
4.1 彎曲型光纖感測器高溫量測實驗
4.1.1 彎曲型光纖感測器之高溫量測
4.1.2 彎曲型光纖感測器高溫量測之實驗結果
4.1.3 彎曲型光纖感測器高溫量測之實驗結果分析
4.2 彎曲型光纖感測器生醫量測實驗
4.2.1 彎曲型光纖感測器之胃泌素-17量測
4.2.2 彎曲型光纖感測器胃泌素-17量測之第一階段實驗結果
4.2.3 彎曲型光纖感測器胃泌素-17量測之第二階段實驗結果分析
4.3 彎曲型光纖感測器濕度量測實驗
4.3.1 彎曲型光纖感測器之濕度量測
4.3.2 彎曲型光纖感測器濕度量測之實驗結果
4.3.3 彎曲型光纖感測器濕度量測之實驗結果分析
第五章 結論
5.1 彎曲型光纖感測器高溫量測實驗結論
5.2 彎曲型光纖感測器生醫量測實驗結論
5.3 彎曲型光纖感測器濕度量測實驗結論
參考文獻

[1]C.-W. Wu, K.-C. Liu, and C.-C. J. I. S. J. Chiang, "A novel U-shaped and microchanneled optical fiber temperature sensor fabricated by LIGA-like process," IEEE Sensors Journal, vol. 17, no. 17, pp. 5444-5449, 2017.
[2]A. Leal-Junior, A. Frizera-Neto, C. Marques, and M. J. J. S. Pontes, "A polymer optical fiber temperature sensor based on material features," Sensors, vol. 18, no. 1, p. 301, 2018.
[3]T. Zhu, T. Ke, Y. Rao, and K. S. J. O. C. Chiang, "Fabry–Perot optical fiber tip sensor for high temperature measurement," Optics Communications, vol. 283, no. 19, pp. 3683-3685, 2010.
[4]H. Sun, M. Hu, Q. Rong, Y. Du, H. Yang, and X. J. O. C. Qiao, "High sensitivity optical fiber temperature sensor based on the temperature cross-sensitivity feature of RI-sensitive device," Optics Communications, vol. 323, pp. 28-31, 2014.
[5]M. M. Noor et al., "High sensitivity of balloon-like bent MMI fiber low-temperature sensor," IEEE Photonics Technology Letters, vol. 27, no. 18, pp. 1989-1992, 2015.
[6]D. Monzón-Hernández, V. P. Minkovich, and J. J. I. P. T. L. Villatoro, "High-temperature sensing with tapers made of microstructured optical fiber," IEEE Photonics Technology Letters, vol. 18, no. 3, pp. 511-513, 2006.
[7]X. Peng, Y. Cha, H. Zhang, Y. Li, and J. J. O. Ye, "Light intensity modulation temperature sensor based on U-shaped bent single-mode fiber," Optik, vol. 130, pp. 813-817, 2017.
[8]Q. Lin et al., "Ordinary Optical Fiber Sensor for Ultra-High Temperature Measurement Based on Infrared Radiation," Sensors, vol. 18, no. 11, p. 4071, 2018.
[9]W. Chen, Z. Chen, Y. Zhang, H. Li, and Y. J. O. F. T. Lian, "Agarose coated macro-bend fiber sensor for relative humidity and temperature measurement at 2 μm," Optical Fiber Technology, vol. 50, pp. 118-124, 2019.
[10]C. G. Danny, A. Subrahmanyam, and V. J. J. o. R. S. Sai, "Development of plasmonic U‐bent plastic optical fiber probes for surface enhanced Raman scattering based biosensing," Journal of Raman Spectroscopy, vol. 49, no. 10, pp. 1607-1616, 2018.
[11]H.-Y. Wen, C.-W. Huang, Y.-L. Li, J.-L. Chen, Y.-T. Yeh, and C.-C. J. S. Chiang, "A Lamping U-shaped fiber biosensor detector for MicroRNA," Sensors, vol. 20, no. 5, p. 1509, 2020.
[12]S. K. Srivastava, V. Arora, S. Sapra, and B. D. J. P. Gupta, "Localized surface plasmon resonance-based fiber optic U-shaped biosensor for the detection of blood glucose," Plasmonics, vol. 7, no. 2, pp. 261-268, 2012.
[13]A. d. S. Arcas, F. d. S. Dutra, R. C. Allil, and M. M. J. S. Werneck, "Surface plasmon resonance and bending loss-based U-shaped plastic optical fiber biosensors," Sensors, vol. 18, no. 2, p. 648, 2018.
[14]B. J. S. Gupta and A. B. Chemical, "A novel probe for a fiber optic humidity sensor," Sensors and Actuators B: Chemical, vol. 80, no. 2, pp. 132-135, 2001.
[15]Y. Zhao, Y. Peng, M.-q. Chen, R.-J. J. S. Tong, and A. B. Chemical, "Humidity sensor based on unsymmetrical U-shaped microfiber with a polyvinyl alcohol overlay," Sensors and Actuators B: Chemical, vol. 263, pp. 312-318, 2018.
[16]Y. Peng, Y. Zhao, X.-g. Hu, M.-q. J. S. Chen, and A. B. Chemical, "Humidity sensor based on unsymmetrical U-shaped twisted microfiber coupler with wide detection range," Sensors and Actuators B: Chemical, vol. 290, pp. 406-413, 2019.
[17]Y. Zhao, R.-j. Tong, M.-Q. Chen, F. J. S. Xia, and A. B. Chemical, "Relative humidity sensor based on hollow core fiber filled with GQDs-PVA," Sensors and Actuators B: Chemical, vol. 284, pp. 96-102, 2019.
[18]H.-Y. Wen, Y.-C. Liu, C.-C. J. S. Chiang, and A. B. Chemical, "The use of doped conductive bionic muscle nanofibers in a tennis racket–shaped optical fiber humidity sensor," Sensors and Actuators B: Chemical, vol. 320, p. 128340, 2020.
[19]T. L. Singal, Optical fiber communications: principles and applications. Cambridge University Press, 2016.
[20]A. Harris and P. J. J. o. L. t. Castle, "Bend loss measurements on high numerical aperture single-mode fibers as a function of wavelength and bend radius," Journal of Lightwave technology, vol. 4, no. 1, pp. 34-40, 1986.
[21]H. J. J. o. L. t. Renner, "Bending losses of coated single-mode fibers: a simple approach," Journal of Lightwave technology, vol. 10, no. 5, pp. 544-551, 1992.