中文摘要 II
Abstract IV
表目錄 XII
圖目錄 XIII
第一章 緒論 1
1.1細菌 1
1.1.1細菌的威脅 2
1.1.2細菌貼附與生物膜之形成 4
1.2抗菌表面的設計 5
1.2.1防汙表面 6
1.2.1.1超親水性表面 6
1.2.1.2超疏水性表面 8
1.2.1.3奈米地形 10
1.2.2殺菌劑 13
1.2.3殺菌表面 16
1.2.4複合式殺菌 18
1.3殼聚醣 20
1.4文獻回顧 22
1.5研究動機與目的 26
第二章 實驗藥品與儀器 28
2.1實驗藥品 28
2.1.1製備殼聚醣膜 28
2.1.2氧化氯測定 28
2.1.3抗菌測試 28
2.2實驗器材 29
2.3實驗耗材 30
2.4實驗儀器與原理 31
2.4.1水接觸角量測儀 32
2.4.2傅立葉轉換紅外線光譜儀 33
2.4.3掃描式電子顯微鏡 34
2.4.4雷射共軛焦顯微鏡 35
2.4.5萬能試驗機 36
2.4.6恆電位/電流儀 36
2.5溶液配置 37
第三章 實驗方法 40
3.1實驗架構 40
3.2疏水化及氯化的殼聚醣薄膜製備 42
3.3具奈米地形及疏水化殼聚醣製備 43
3.4表面特徵 45
3.4.1水接觸角量測儀 45
3.4.2傅立葉轉換紅外線光譜儀 45
3.4.3掃描式電子顯微鏡 46
3.4.4聚焦離子束系統和穿透式電子顯微鏡 46
3.5材料性質 46
3.5.1氯含量檢測 46
3.5.2氯再生 47
3.5.3分解速率 47
3.5.4機械性質 47
3.6抗菌測試 48
3.6.1細菌貼附 48
3.6.2接觸式殺菌 49
3.6.3抑制圈 49
3.7耐腐蝕 50
3.8統計分析 50
第四章 協同疏水化及氯化的殼聚醣薄膜之表面改質 51
4.1疏水化殼聚醣薄膜的表面表徵 51
4.1.1表面水接觸角 51
4.1.2化學結構分析 52
4.2疏水化殼聚醣薄膜對細菌附著的影響 53
4.3疏水化殼聚醣薄膜對氯化的影響 54
4.4氯化樣品的殺菌性能 55
4.5存放30天的殺菌性及氯釋放 56
4.6氯再生的能力 57
4.7薄膜的降解速率 58
4.8薄膜的機械性質 59
4.9討論 61
4.10結論 62
第五章 奈米地形化及烷基化殼聚醣的表面改質用以改善細菌附著及
腐蝕發生 78
5.1塗層表面表徵 78
5.1.1表面形貌 78
5.1.2表面性質分析 80
5.1.3表面親疏水性 80
5.2烷基醛/奈米地形殼聚醣對細菌附著影響 81
5.3烷基醛/奈米地形殼聚醣抗腐蝕性能 82
5.4結論 84
第七章 參考文獻 100

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