|
1. Ao, Z.H.; Xu, Z.H.; Lu, Z.M.; Xu, H.Y.; Zhang, X.M.; Dou, W.F. Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases. Journal of Ethnopharmacology 121, 194–212 (2009). 2. http://www.aenews.com.tw/fxw290wgi0.html. 3. Madamanchi, G; Tzeng, Y.M. Review of pharmacological effects of Antrodia camphorata and its bioactive compounds. Evidence-Based Complementary and Alternative Medicine, 1-17 (2011). 4. Wu, S.H.; Yu, Z.H.; Dai, Y.C.; Chen, C.T.; Su, C.H.; Chen, L.C.; Hsu, W.C.; Hwang, G.Y. Taiwanofungus, a polypore new genus. Fungal Science 19, 109–116 (2004). 5. 邱永年, 張光雄《原色台灣藥用植物圖鑑(6)》,南天書局,台北, 第六冊,5,(2001). 6. Male, K.B.; Rao, Y.K.; Tzeng, Y.M.; Montes, J.; Kamen, A.; Luong, J. H.T. Probing inhibitory effects of Antrodia camphorata isolates using insect cell-based impedance spectroscopy: inhibition vs chemical structure. Chemical Research in Toxicology 21, 2127–2133 (2008). 7. Yeh, C.T.; Rao, Y.K.; Yao, C.J.; Yeh, C.F.; Li, C.H.; Chuang, S.E.; Luong, J.H.T.; Lai, G.M.; Tzeng, Y.M. Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells. Cancer Letters 285, 73–79 (2009). 8. Chen, C.H.; Yang, S.W.; Shen. Y.C. New steroid acids from Antrodia cinnamomea. a fungal parasite of Cinnamomum micranthum. Journal of Natural Products 58, 1655–1661 (1995). 9. Chen, J.J.; Lin, W.J.; Liao, C.H.; Shieh. P.C. Anti-inflammatory benzenoids from Antrodia camphorata. Journal of Natural Products 70, 989–992 (2007). 10. Cherng, I.H.; Wu, D.P.; Chiang, H.C. Triterpenoids from Antrodia cinnamomea. Phytochemistry 41, 263–267 (1996). 11. Chien, S.C.; Chen, M.L.; Kuo, H.T.; Tsai, Y.C.; Lin, B.F.; Kuo. Y.H. 108 Anti-inflammatory activities of new succinic and maleic derivatives from the fruiting body of Antrodia camphorata. Journal of Agricultural and Food Chemistry 56, 7017–7022 (2008). 12. Shen, Y.C.; Yang, S.W.; Lin, C.S.; Chen, C.H.; Kuo, Y.H.; Chen, C.F. Zhankuic acid F: a new metabolite from a formosan fungus Antrodia cinnamomea. Planta Medica 63, 86–88 (1997). 13. Shen, Y.C.; Wang, Y.H.; Chou, Y.C.; Chen, C.F.; Lin, L.C.; Chang, T. T.; Tien, J.H. Cheng, C.J. Evaluation of the anti-inflammatory activity of zhankuic acids isolated from the fruiting bodies of Antrodia camphorata. Planta Medica 70, 310–314 (2004). 14. Shen, C.C.; Kuo, Y.C.; Huang, R.L.; Lin, L.C.; Don, M.J.; Chang, T.T.; Chou, C.J. New ergostane and lanostane from Antrodia camphorata. The Journal of Chinese Medicine 14, 247–58 (2003). 15. Shen, Y.C.; Chen, C.F.; Wang, Y.H.; Chang, T.T.; Chou, C.J. Evaluation of the immuno-modulating activity of some active principles isolated from the fruiting bodies of Antrodia camphorata. Chinese Pharmaceutical Journal 55, 313–318 (2003). 16. Cherng, I.H.; Chiang, H.C.; Cheng, M.C.; Wang, Y.U. Three new triterpenoids from Antrodia cinnamomea. Journal of Natural Products 58, 365–371 (1995). 17. Chen, C.C.; Shiao, Y.J.; Lin, R.D.; Shao, Y.Y.; Lai, M.N.; Lin, C.C.; Ng, L.T.; Kuo. Y.H. Neuroprotective diterpenes from the fruiting body of Antrodia camphorata. Journal of Natural Products 69, 689–691 (2006). 18. Chiang, C.H.; Wu, D.P.; Cherng, I.W.; Ueng, U.C. A sesquiterpene lactone, phenyl and biphenyl compounds from Antrodia cinnamomea. Phytochemistry 39, 613–616 (1995). 19. Lien, H.M.; Lin, H.W.; Wang, Y.J.; Chen, L.C.; Yang, D.Y.; Lai, Y.Y.; Ho, Y.S. Inhibition of anchorage-independent proliferation and G0/G1 cell cycle regulation in human colorectal carcinoma cells by 4,7-dimethoxy-5-methyl-l,3-benzodioxole isolated from the fruiting 109 body of Antrodia camphorate. Evidence-Based Complementary and Alternative Medicine 17, 1-9 (2009). 20. Huang, K.F.; Huang, W.M.; Chiang, H.C. Phenyl compounds from Antrodia cinnamomea. Chinese Pharmaceutical Journal 53, 327–331 (2001). 21. Wu, M.D.; Cheng, M.J.; Wang, B.C.; Wang, W.Y.; Lai, J.T.; Yuan, G.F. Chemical constituents from the mycelia of Antrodia cinnamomea. Journal of the Chilean Chemical Society 52, 1338–1340 (2007). 22. Wu, D.P.; Chiang, C.H. Constituents of Antrodia cinnamomea. Journal of the Chinese Chemical Society 42, 797–800 (1995). 23. Hattori, M.; Sheu, C.C. Compounds from Antrodia camphorata having anti-inflammatory and anti-tumor activity. United States, 9-19 (2006). 24. Phuong, D.T.; Ma, C.M.; Hattori, M.; Jin, J.S. Inhibitory effects of antrodins A-E from Antrodia cinnamomea and their metabolites on hepatitis c virus protease. Phytotherapy Research 23, 582–584 (2009). 25. Wu, M.D.; Cheng, M.J.; Wang, B.C.; Yech, Y.J.; Lai, J.T.; Kuo, Y.H. Yuan, G.F.; Chen, I.S. Maleimide and maleic anhydride derivatives from the mycelia of Antrodia cinnamomea and their nitric oxide inhibitory activities in macrophages. Journal of Natural Products 71, 1258–1261 (2008). 26. Chen, C.C.; Chyau, C.C.; Hseu. T.H. Production of a COX-2 inhibitor, 2,4,5-trimethoxybenzaldehyde, with submerged cultured Antrodia camphorata. Letters in Applied Microbiology 44, 387–392 (2007). 27. Chen, Y.J.; Cheng, P.C.; Lin, C.N.; Liao, H.F.; Chen, Y.Y.; Chen, C.C.; Lee, K.M. Polysaccharides from Antrodia camphorata mycelia extracts possess immunomodulatory activity and inhibits infection of Schistosoma mansoni. International Immunopharmacology 8, 458–467 (2008). 28. Lu, M.K.; Cheng, J.J.; Lai, W.L.; Lin, Y.R.; Huang, N. K. Adenosine as an active component of Antrodia cinnamomea that prevents rat PC12 cells from serum deprivation-inducedapoptosis through the activation of 110 adenosine A2A receptors. Life Sciences 79, 252–258, (2006). 29. Chiu. H.H. Phylogenetic analysis of Antrodia species and Antrodia camphorata inferred from internal transcribed spacer region. Antonie van Leeuwenhoek 91, 267–276 (2007). 30. Lee, T.H.; Lee, C.K.; Tsou, W.L.; Liu, S.Y.; Kuo, M.T.; Wen. W.C. A new cytotoxic agent from solid-state fermented mycelium of Antrodia camphorata. Planta Medica 73, 1412–1415 (2007). 31. Chang, J.M.; Lee, Y.R.; Hung, L.M.; Lin, S.Y.; Kuo, M.T.; Wen, W.C.; Chen, P. An extract of Antrodia camphorata mycelia attenuates the progression of nephritis in systemic lupus erythematosus-prone NZB/W F1 mice. Evidence-Based Complementary and Alternative Medicine, 1-7 (2008). 32. Yang, S.S.; Wang, G.J.; Wang, S.Y.; Lin, Y.Y.; Kuo, Y.H.; Lee, T.H. New constituents with iNOS inhibitory activity from mycelium of Antrodia camphorata. Planta Medica 75, 512–516 (2009). 33. Geethangili, M.; Fang, S.H.; Lai, C.H.; Rao, Y.K.; Lien, H.M.; Tzeng, Y.M. Inhibitory effect of Antrodia camphorata constituents on the Helicobacter pylori-associated gastric inflammation. Food Chemistry 119, 149–153 (2010). 34. Wang, G.J.; Tseng, H.W.; Chou, C.J.; Tsai, T.H.; Chen, C.T.; Lu. M.K. The vasorelaxation of Antrodia camphorata mycelia: involvement of endothelial Ca2+-NO-cGMP pathway. Life Sciences 73, 2769–2783 (2003). 35. Chen, C.J.; Su, C.H.; Lan, M.H. Study on solid cultivation and bioactivity of Antrodia camphorata. Fungal Sciences 16, 65–72, (2001). 36. Shen, C.C.; Yang, H.C.; Huang, R.L.; Chen, J.C.; Chen, C.C. Anti-HBV principle from the culture broth of Antrodia camphorata (strain # CCRC-35396). The Journal of Chinese Medicine 16, 57–61, (2005). 37. Huang, R.L.; Huang, Q.; Chen, C.F.; Chang, T.T.; Chou, C.J. Anti-viral 111 effects of active compounds from Antrodia camphorata on wild-type and lamivudine-resistant mutant HBV. Chinese Pharmaceutical Journal 55, 371–379 (2003). 38. Liu, S.Y.; Kuo, M.T.; Wen, W.C. Inhibition of hepatitis B virus by cyclohexenone compounds from Antrodia camphorata. United States (2009). 39. Hseu, Y.C.; Chang, W.C.; Hseu, Y.T.; Lee, C.Y.; Yech, Y.J.; Chen, P.C. Chen, J.Y.; Yang, H.L. Protection of oxidative damage by aqueous extract from Antrodia camphorata mycelia in normal human erythrocytes. Life Sciences 71, 469–482 (2002). 40. Hseu, Y.C.; Yang, H.L.; Lai, Y.C.; Lin, J.G.; Chen, G.W.; Chang, Y.H. Induction of apoptosis by Antrodia camphorata in human premyelocytic leukemia HL-60 cells. Nutrition and Cancer 48, 189–197 (2004). 41. Wu, H.; Pan, L.Y.; Yao, C.; Chang, S.S.; Li, S.L.; Wu, T.F. Proteomic analysis of the effect of Antrodia camphorata extract on human lung cancer A549 cell. Proteomics 6, 826–835 (2006). 42. Hsu, Y.L.; Kuo, Y.C.; Kuo, P.L.; Ng, L.T.; Kuo, Y.H.; Lin, C.C. Apoptotic effects of extract from Antrodia camphorata fruiting bodies in human hepatocellular carcinoma cell lines. Cancer Letters 221, 77–89 (2005). 43. Kuo, P.L.; Hsu, Y.L.; Cho, C.Y.; Ng, L.T.; Kuo, Y.H.; Lin. C.C. Apoptotic effects of Antrodia cinnamomea fruiting bodies extract are mediated through calcium and calpain dependent pathways in Hep 3B cells. Food and Chemical Toxicology 44, 1316–1326 (2006). 44. Hsu, Y.L.; Kuo, P.L.; Cho, C.Y.; Ni, W.C.; Tzeng, T.F.; Ng, L.T.; Kuo, Y.H.; Lin, C.C. Antrodia cinnamomea fruiting bodies extract suppresses the invasive potential of human liver cancer cell line PLC/PRF/5 through inhibition of nuclear factor κB pathway. Food and Chemical Toxicology 45, 1249–1257 (2007). 45. Hseu, Y.C.; Wu, F.Y.; Wu, J.J.; Chen, J.Y.; Chang, W.H.; Lu, F.J.; Lai, 112 Y.C.; Yang, H.L. Anti-inflammatory potential of Antrodia camphorata through inhibition of iNOS, COX-2 and cytokines via the NF-κB pathway. International Immunopharmacology 5, 1914–1925 (2005). 46. Liu, D.Z.; Liang, H.J.; Chen, C.H.; Su, C.H.; Lee, T.H.; Huang, C.T.; Hou, W.C.; Lin, S.Y.; Zhong, W.B.; Lin, P.J.; Hung, L.F.; Liang, Y. C. Comparative anti-inflammatory characterization of wild fruiting body, liquidstate fermentation, and solid-state culture of Taiwanofungus camphoratus in microglia and the mechanism of its action. Journal of Ethnopharmacology 113, 45–53 (2007). 47. Kuo, M.C.; Chang, C.Y.; Cheng, T.L.; Wu, M.J. Immunomodulatory effect of Antrodia camphorata mycelia and culture filtrate. Journal of Ethnopharmacology 120, 196–203 (2008). 48. Chen, J.C.; Chen, C.N.; Sheu, S.J.; Hu, M.L. Liver-caring medicine containing Antrodia camphorata. United States, 6-19 (2003). 49. Song, T.Y.; Yen, G.C. Antioxidant properties of Antrodia camphorata in submerged culture. Journal of Agricultural and Food Chemistry 50, 3322–3327 (2002). 50. Hsiao, G.; Shen, M.Y.; Lin, K.H.; Lan, M.H.; Wu, L.Y.; Chou, D.S.; Lin, C.H.; Su, C.H.; Sheu, J.R. Antioxidative and hepatoprotective effects of Antrodia camphorata extract. Journal of Agricultural and Food Chemistry 51, 3302–3308 (2003). 51. Mau, J.L.; Huang, P.N.; Huang, S.J.; Chen, C.C. Antioxidant properties of methanolic extracts from two kinds of Antrodia camphorata mycelia. Food Chemistry 86, 25–31 (2004). 52. Shu, C.H.; Lung, M.Y. Effect of culture pH on the antioxidant properties of Antrodia camphorata in submerged culture. Journal of the Chinese Institute of Chemical Engineers 39, 1–8 (2008). 53. Yang, H.L.; Hseu, Y.C.; Chen, J.Y.; Yech, Y.J.; Lu, F.J.; Wang, H.H.; Lin, P.S.; Wang, B.C. Antrodia camphorata in submerged culture protects low density lipoproteins against oxidative modification. American Journal of Chinese Medicine 34, 217–231 (2006). 113 54. Hseu, Y.C.; Chen, S.C.; Yech, Y.J.; Wang, L.; Yang. H.L. Antioxidant activity of Antrodia camphorata on free radical-induced endothelial cell damage. Journal of Ethnopharmacology 118, 237–245 (2008). 55. Huang, S. J.; Mau. J.L. Antioxidant properties of methanolic extracts from Antrodia camphorata with various doses of γ-irradiation. Food Chemistry 105, 1702–1710 (2007). 56. Dai, Y.Y.; Chuang, C.H.; Tsai, C.C.; Sio, H.M.; Huang, S.C.; Chen, J. C.M.; Hu, L. The protection of Antrodia camphorata against acute hepatotoxicity of alcohol in rats. Journal of Food and Drug Analysis 11, 177–185 (2003). 57. Lu, Z.M.; Tao, W.Y.; Zou, X.L.; Fu, H.Z.; Ao, Z.H. Protective effects of mycelia of Antrodia camphorata and Armillariella tabescens in submerged culture against ethanol induced hepatic toxicity in rats. Journal of Ethnopharmacology 110, 160–164 (2007). 58. Chang, T.T.; Chou, W.N. Antrodia cinnamomea sp. nov. on Cinnamomum kanehirai in Taiwan. Mycological Research 99, 756–758 (1995). 59. Wu, S.H.; Ryvarden, L.; Chang. T.T. Antrodia camphorata (’niu-chang-chih’), new combination of a medicinal fungus in Taiwan. Botanical Bulletin of Academia Sinica 38, 273–275 (1997). 60. Tsai, Z.T.; Liaw, S. L. The use and the effect of Ganoderma, San Yun Press, Taichung, Taiwan (1985). 61. Zang, M.; Su, Q.H. Ganoderma comphoratum, a new taxon in genus Ganoderma from Taiwan. China. ActaBotanica Yunnanica 12, 395–396 (1990). 62. Chang, T.T.; Chou, W.N. Antrodia cinnamomea reconsidered and A. salmonea sp. nov. on Cunninghamia konishii in Taiwan. Botanical Bulletin of Academia Sinica 45, 347–352 (2004). 63. Hawksworth, D.L.; Kirk, P.M.; Sutton, B.C.; Pegler, D.N. Ainsworth and Bisby’s Dictionary of the Fungi. International Mycological Institute, Egham, UK, 8 (1995). 114 64. Su, C.H. Health Guardian Angel: Antrodia camphorata, EKS Book Publishing, Taipei, Taiwan, 1st ed. (2002). 65. Chen, J.C. King of Ganoderma: Antrodia camphorata in Taiwan, Yuen Chi Jai Book Publishing, Taipei, Taiwan, 2nd ed. (2008). 66. Chen, C.C.; Liu, Y.W.; Ker, Y.B.; Wu, Y.Y.; Lai, E.Y.; Chyau, C.C.; Hseu, T.H.; Peng, R. Y. Chemical characterization and anti-inflammatory effect of polysaccharides fractionated from submerge-cultured Antrodia camphorata mycelia. Journal of Agricultural and Food Chemistry 55, 5007–5012 (2007). 67. Paterson, R.R.M. Ganoderma—a therapeutic fungal biofactory. Phytochemistry 67, 1985–2001 (2006). 68. Wu, S.J.; Leu, Y.L.; Chen, C.H.; Chao, C.H.; Shen, D.Y.; Chan, H.H.; Lee, E.; Wu, T.S.; Wang, Y.H.; Shen, Y.C.; Qian, K.; Bastow, K.F.; Lee, K.H. Camphoratins A–J, potent cytotoxic and anti-inflammatory triterpenoids from the fruiting body of Taiwanofungus camphoratus. Journal of Natural Products 73, 1756–1762 (2010). 69. Mahajna, J.; Dotan, N.; Zaidman, B.Z.; Petrova, R.D.; Wasser, S.P. Pharmacological values of medicinal mushrooms for prostate cancer therapy: the case of Ganoderma lucidum. Nutrition and Cancer 61, 16–26 (2009). 70. Lindequist, U.; Niedermeyer, T.H.J.; Julich; W.D. The pharmacological potential of mushrooms. Evidence-Based Complementary and Alternative Medicine 2, 285–299 (2005). 71. Rao, Y.K.; Fang, S.H.; Tzeng, Y.M. Evaluation of the anti-inflammatory and anti-proliferation tumoral cells activities of Antrodia camphorata, Cordyceps sinensis and Cinnamomum osmophloeum bark extracts. Journal of Ethnopharmacology 114, 78–85 (2007). 72. Wu, S.H.; Yu, S.H.; Dai, Y.H.; Chen, C.T.; Su, C.H.; Chen, L.C.; Hsu, W.C.; Hwang, Y.H. Taiwanofungus, a polypore new genus. Fungal Science 19, 109–116 (2004). 115 73. Han, J.Y.; In, J.G.; Kwon, Y.S.; Choi, Y. E. Regulation of ginsenoside and phytosterol biosynthesis by RNA interferences of squalene epoxidase gene in Panax ginseng. Phytochemistry 71, 36-46 (2010). 74. Pluta, P.L.; Crespi, H.L.; Klein, M.; Blake, M.I.; Studier, M.H.; Katz, J.J. Biosynthesis of deuterated riboflavin: structure determination by NMR and mass spectrometry. Journal of Pharmaceutical Sciences 65, 362-366 (1976). 75. Manitto. Biosynthesis of Natural products, 319 (1981). 76. Cheng, J.Y.W. ; Lau, A.P.S. ; Fang, M. Assessment of the atmospheric fungal prevalence through field ergosterol measurement I--Determination of the specific ergosterol content in common ambient fungal spores and yeast cells. Atmospheric Environment 42, 5526-5533 (2008). 77. Chiang, P.C.; Lin, S.C.; Pan, S.L.; Kuo, C.H.; Tsai, I.L.; Kuo, M.T.; Wen, W.C.; Chen, P.; Guh, J.H. Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: A crucial role of AMPK and mTOR pathways. Biochemical Pharmacology 79, 162–171 (2010). 78. Kleinert, H.; Schwarz, P.M.; Forstermann, U. Regulation of expression of inducible nitric oxide synthase. Biological Chemistry 384, 1343-1364 (2003). 79. Muijsers, P.B.R.; Folkerts, G.; Henricks, P.A.J.; Sadeghi-Hashjin, G.; Nijkamp, F.P. Peroxynitrite: a two-faced metabolite of NO. Life Science 60, 1833-1845 (1997). 80. Peter, P. The immune system. Garland Publishing, London, p.201-219 (2000). 81. Tracey, K.J.; Cerami, A. Tumor necrosis factor, other cytokines and disease. Annual Review of Cell and Developmental Biology 9, 317-343 (1993). 82. Nathan, C.F. Secretory products of macrophages. The Journal of Clinical Investigation 79, 319-323 (1987). 116 83. Zelnickova, P.; Matiasovic, J.; Pavlova, B.; Kudlackova, H.; Kovaru, F.; Faldyna, M. Quantitative nitric oxide production by rat, bovine and porcine macrophages. Nitric Oxide 19, 36-41 (2008). 84. Chen, Y.C.; Yang, L.L.; Lee, T.J.F. Oroxylin A inhibition of lipopolysaccharide-induced iNOS and COX-2 gene expression via suppression of nuclear factor-[kappa]B activation. Biochemical Pharmacology 59, 1445-1457 (2000). 85. http://burn.fire.net.cn/Article.aspx?ArticleID=355
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