王伯徹、陳啟楨、華傑。1998。食藥用菇類的培養與應用。食品工業發展研究所。p.144-150。
江素瑛、吳焜裕、王秋萍、魏逸傑、施睿宏、高尚德、謝慶良。2002。 樟芝之致基因毒性與抗基因毒性評估。台灣保健食品協會第二屆第二次年會大會議程及論文摘要。p.48。
江素瑛。2001。靈芝與樟芝之安全與毒理。「保健食品」跨部會整合推動委員會。p.64-72。
吳德鵬。1995。樟芝微量成分的研究。國立台灣師範大學化學研究所碩士論文。台北，臺灣。呂鋒洲。2002。牛樟芝各抗腫瘤有效成分的分離、純化，誘發腫瘤凋亡及其作用 機轉的研究。九十一年度保健食品研究開發計畫成果發表會。p.13-16。
宋祖瑩。2003 樟芝深層培養液抗氧化及抗腫瘤特性之研究 國立中興大學食品 科學系博士論文。台中，臺灣。沈立言。2000。牛樟芝菌絲體發酵萃取液對肝臟生理機能性之影響。 89年度保健食品研究開發計畫心得發表會。p.191-198。
林文鑫，陳俊憲，陳勁初，呂鋒州。2000。樟芝液態發酵萃取物對腫瘤細胞株之毒殺性分析。中華民國食品科學技術學會第三十次(第十五屆第二次)會員大會手冊。p.254。
林惠君。2005。薑黃素抗IgE媒介型過敏反應之體外效用評估。國立台灣海洋大學/食品科學研究所碩士論文。基隆，臺灣。邱士峰。2003。甲魚萃取物生體外免疫調節功能評估。國立台灣海洋大學食品科學研究所碩士論文。基隆，臺灣。范真綺。2004。樟芝固態栽培與液態發酵菌絲體之成分及其生物活性之研究。南台科技大學化學工程研究所。台南，臺灣。 高曉薇。1991。台灣靈芝屬新種樟芝之三帖類成分研究。台北醫學院天然物醫學研究所碩士論文。台北，臺灣。曹巧吟。2002。樟芝中免疫調節蛋白的純化與其生理活性之探討 國立臺灣大學園藝學研究所碩士論文。台北，臺灣。張東柱。 1997。牛樟之病害。牛樟生物學及育林技術研討會論文集。林業叢刊 第72號: 127-131。
張中姿。2002。樟芝菌絲體之甲醇萃取部份對人類肝癌細胞株(Hep G2)生長抑制作用的機制探討。國立台灣大學醫學院生物化學劑分子生物學研究所。台北，臺灣。許勝傑、陳清農、陳勁初。2000。樟芝宿主專一性之探討，台灣農業化學與食品科學 38: 533-539。
郭淑卿。2002。樟芝發酵液對大鼠肝臟纖維化及胃腸功能之改善作用。中國醫藥學院中國藥學研究所藥學碩士論文。台中，臺灣。陳秀雯，陳清農，黃仕政，許勝傑，曾虹萍，洪鳴遠，傅麒玲，陳勁初。2002。牛樟芝菌絲體之免疫調節功能評估. 中華民國食品科學技術學會. 第三十二次(第十六屆第二次)會員大會手冊 p. 326.
陳勁初，林文鑫，陳清農，許勝傑，黃仕政，陳炎鍊。2001。台灣特有真菌-樟芝菌絲體之開發。Fung. Sci. 16: 7-22
陳怡欣。200。牛樟芝發酵過濾液對大白鼠肝臟生理機能之影響。中國醫藥學院營養研究所碩士論文。台中，臺灣。陳啟楨。1999。菇類二次代謝物值及其利用。食品工業 31:1-11。黃鈴娟。2000。樟芝與姬松茸之抗氧化性質及其多醣組成分析，國立中興大學食品科學系。台中，臺灣。劉翠玲。 2002。樟芝對倉鼠體內脂質代謝與抗氧化狀態之影響。輔仁大學食品營養學系碩士論文。台北，臺灣。蔡雁暉。2002。樟芝深層培養液極其多醣體之抗氧化特性。國立中興大學食品科學系研究所碩士論文。台中，臺灣。賴宏亮，呂美津，陳武元，莊秀琪。2002。樟芝免疫調節活性之研究。台灣保健食品學會。第二屆第二次年會大會議程及壁報論文摘要。p. 49。
簡秋源、姜宏哲、陳淑貞。1997。牛樟菇培養性狀及其三帖類成分分析之研究。牛樟生物學及育林技術研討會論文集，林業叢刊第72號：133-137。
Adams, J.M., and Cory, S. (1998). The Bcl-2 protein family: arbiters of cell survival. Science 281, 1322-1326.
Agarwal, R. (2000). Cell signaling and regulators of cell cycle as molecular targets for prostate cancer prevention by dietary agents. Biochem. Pharmacol. 60, 1051-1059
Akriviadis, E.A., Llovert, J.M., Efremidies, S.C., Shouval, D., Canelo, R., Ringe, B., and Meyers, W.C. (1998). Hepatocellular carcinoma. Br J Surg. 85, 1319-31
Alblas, J., Slager-Davidov, R., Steenbergh, P.H., Suessenbach J.S. and van, der, Burg, B. (1998). The role of MAP kinase in TPA-mediated cell cycle arrest of human breast cancer cell. Oncogen. 16, 131-139
Bae, Y.S., Kang, M.S., Kang, S.W. Seo, M.S., Baines, I.C., Tekle, E., Chock, P.B. and Rhee, S.G. (1997). Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. J. Biol. Chem. 272, 217-221.
Belka, C., Schmid, B., Marini, P., Durand, E., Rudner, J., Faltin, H., Bamberg, M., Schulze-Osthoff, K. and Budach, W. (2001) Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL. Oncogene 20, 2190–2196
Ben, Z.Z., Majed, Y., Jamal, M., and Solomon, P.W. (2005). Medicinal mushroom modulators of molecular targets as cancer therapeutics. Appl Microbiol Biotechnol. 67, 453-468
Bolondi, L., Sofia, S., Siringo, S., Gaiani, S., Casali, A., Zironi, G., Piscaglia, F., Gramantieri, L., Zanetti, M., and Sherman, M. (2001). Surveillance programme of cirrhotic patients for early diagnosis and treatment of hepatocellular carcinoma: a cost effectiveness analysis. Gut 48, 251-259
Bosch, F.X., Ribes, J., and Borras, J. (1999). Epidemiology of primary liver cancer. Semin Liver Dis. 19, 271－285.
Budihardjo, I., Oliver, H., Lutter, M., Luo, X. and Wang, X. (1999). Biochemical pathways of caspase activation during apoptosis. Annu. Rev. Cell Dev. Biol. 15, 269-290.
Chang, H.L., and Chou, W.N., (1995). Antrodia cinnamomea sp. nov. on Cinnamomum kanehirai in Taiwan. Mycol. Res. 99, 756-758.
Chang, H.L., Chao, G.R., Chen, C.C. and Mau, J.L. (2001). Non-volatile taste components of Agaricus blazei, Antrodia camphorata and Cordyceps militaris mycelia. Food Chem. 74, 203-207.
Chang, T.T., and Chou. W.N., (2004). Antrodia cinnamomea reconsidered and A. saloonea sp. Nov. on Cunninghamia konishii in Taiwan. Bot. Bull. Acad. Sin. 45, 347-352.
Chen, C.H., and Yang, S.W. (1995). New steroid acids from Antrodia cinnamomea a fungal parasite of Cinnamomum micranthum. J. Nat. Prod. 58, 1655-1661
Cherng I.H., and Chiang H.C. (1995). Three new triterpenoids from Antrodia cinnamomea. J. Nat. Prod. 58, 365-371.
Cherng, I.H., Wu, D.P., and Chiang, H.C. (1996). Triterpenoids from Antrodia cinnamomea. Phytochemistry 41, 263-267
Cuello, M., Ettenberg, S.A., Nau, M.M. and Lipkowitz, S. (2001). Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells. Gynecol. Oncol. 81, 380–390
Degli-Esposti, M.A., Dougall, W.C., Smolak, P.J., Waugh, J.Y., Smith, C.A., and Goodwin, R.G. (1997). The novel receptor TRAILR4 induces NF-kappa B and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity 7, 813-820.
Degli-Esposti, M.A., Smolak, P.J., Walczak, H. Waugh, J., Huang, C.P., DuBose, R.F., Goodwin, R.G., and Smith, C.A. (1997). Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family. J. Exp. Med. 186, 1165-1170.
Desagher, S. and Martinou, J.C. (2000). Mitochondria as the central control point of apoptosis. Trends. Cell. Biol. 10, 369-377.
Earnshaw, W.C., Martins, L.M. and Kaufmann, S.H. (1999). Mammalian caspase: structure, activation, substrates, and functions during apoptosis. Annu. Rev. Biochem. 68, 383-424
Emery, J.G., McDonnell, P., Burke, M.B., Deen, K.C., Lyn, S., Silverman, C., Dul, E., Appelbaum, E.R., DiPrinzio, R. (1998). Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J. Biol. Chem. 273, 14363-14367.
Eo, S.K., Ki, Y.S., Lee, C.K., and Han, S.S. (1999). Antiherpetic activities of various protein bound polysaccharide isolated from Ganoderma lucidum. J Ethnopharma. 72, 475-481.
Fattovich, G., Giustina, G., Schalm, S.W., Hadziyannis, S., Sanchez-Tapias, J., Almasio, P., Christensen, E., Krogsgaard, K., Degos, F., Carneiro de Moura M., et al. (1995). Occurrence of hepatocellular carcinoma and decompensation in western European patients with cirrhosis type B. The EUROHEP Study Group on Hepatitis B Virus and Cirrhosis. Hepatology. 21,77-82.
Fumarola, C. and Guidotti, G.G. (2004). Stress-induced apoptosis: toward symmetry with receptor-mediated cell death. Apoptosis 9, 77-82.
Ganten, T.M., Hass, T.L., Sykora, J., Stahl, H., Sprick, M.R. (2004) Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitization of human hepatocellular carcinoma cell to TRAIL-induced apoptosis by chemotherapeutic drugs. Cell Death Differ. 11, 86-96
Gliniak, B., and Le, T., (1999). Tumor necrosis factor-related apoptosis-inducing ligand’s antitumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11. Cancer. Res. 59, 6153–6158
Gores, G.J. and Kaufmann, S.H. (2001). Is TRAIL hepatotoxic? Hepatology 34, 3–6
Greuter, W., Mcneill, J., Barrie, F.R., Burdet, H.M., Demoulin, V., Filgueiras T.S., Nicolson, D.H., Silva, P.C. Skog, J.E., Turland, N.J., and Hawksworth. (2000). In ternational Code of Botanical Nomenclature (St Louis Code). Regnum Vegetabile 138. Konigstein: Koeltz Scientific Books.
Guyton, K.Z., Liu, Y., Gorospe M., Xu Q. and Holbrook N.J. (1996). Activation of mitogen-activated protein kinase by H2O2: role in cell survival following oxidant injury. J. Biol. Chem. 271,4138-4142.
Hengartner, M.O. (2000). The biochemistry of apoptosis. Nature 407, 770-776.
Hiroo, H., Yasuaki, Y., Kanki, K., Masahiko, H., Masami, I., Tatsushi Y., Toshiyuki, S., Takashi, K., Toh-Seok, K., Ken, M., Kazuyuki, S., Kazuto, T., Norihiko, A., Kunihiro, T., Masato, M., Nobuyuki, T., and Shimeru, K. (2006) Dihydroflavonol BB-1, an extract of natural plant Blumea balsamifera,abrogates TRAIL resistance in leukemia cells. Blood 107, 679-688
Hong, W. K., and Spon, M. B. (1997). Recent advances in chemoprevention of cancer. Science 278, 1073-1077.
Hseu Y. C., Chang W. C., Hseu Y. T., Lee C. Y. Yech Y. J., Chen P. C., Chen J. Y. and Yang H. L. (2002). Protection of oxidative damage by aqueous extract from Antrodia camphorata mycelia in normal human erythrocytes. Life. Sci. 71, 469-482.
Hsiao G, Shen MY, Lin KH, Lan MH, Wu LY, Chou DS, et al. (2003) Antioxidative and hepatoprotective effects of Antrodia camphorate extract. J Agric Food Chem. 51, 3302–3308.
Huang, L.C., Huang, S.J., Chen, C.C. and Mau, J.L. (1999). Antioxidant properties of Antrodia camphorata. Proceedings of 3rd International Conference on Mushroom Biology & Mushroom Products. p275-283
Hyslop, P. A., Hinshaw, D.B., Halsey, W.A., Schraufstätter, R.D., Spragg, R.G., Jackson, J.H. and Cochrane, C.G. (1988). Mechanisms of oxidant- mediated cell injury. J. Biol. Chem. 263, 1665-1675.
Nakamura N, Hirakawa A, Gao JJ, Kakuda H, Shiro M, Komatsu Y, et al. (2004) Five new maleic and succinic acid derivatives from the mycelium of Antrodia camphorata and their cytotoxic effects on LLC tumor cell line. J Nat Prod. 67, 46– 8.
Kelekar, A. and Thompson, C.B. (1998). Bcl-2 family proteins: the role of the BH3 domain in apoptosis. Trens. Cell. Biol. 8, 324.-333
Kidd V.J. (1998). Proteolytic activities that mediate apoptosis. Annu. Rev. Physiol. 60, 533-73.
Lee, I.H., Huang, R.L., Chen, C.T., Chen, H.C., Hsu, W.C., and Lu, M.K., (2002). Antrodia camphorata polysaccharides exhibit anti-hepatitis B virus effects. FEMS. Microbiol. Lett. 209, 63-7.
Liu, J.J., Huang, T.S., Hus, M.L., Chen, C.C., Lin, W.S., Lu, F.J., Chang, W.H., (2004). Antitumor effects of the partially purified polysaccharides from Antrodia camphorata and the mechanism of its action. Toxicol. Appl. Pharmacol. 201, 186-93.
Liu, X., Zou, H., Slaughter, C. and Wang, X. (1997). DEF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89, 175-84.
Manna, S.K., Zhang, H.J., Yan, T., Oberley, L.W. and Aggarwal, B.B. (1998). Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis activation of nuclear transcription factor-b and activated prtein-1. J. Biol. Chem. 273, 13245-54.
Marsters, S.A., Sheridan, J.P., Pitti, R.M., Huang, A., Skubatch, M., Baldwin, D., Yuan, J., Gurney, A., Goddard, A.D., Godowski, P., and Ashkeanzi, A. (1997). A novel receptor for Apo2L/TRAIL contains a truncated death domain. Curr. Boil. 7, 1003-1006.
Mates, J. M., and Sánchez-Jiménez, F.M. (2000). Review: role of reactive oxygen species in apoptosis: implications for cancer therapy. Int. J. Biochem. 32,157-170.
Mwrck, E. Dyeing reagents for thin layer and paper chromatography. 1976, Darmstadt, Germany
Mizuno, T., (1995)a. Biocctive biomolecules of mushrooms: food function and medicinal effect of mushroom fungi. Food. Rev. Int. 11,7-21
Mizuno, T. (1995)b. Yamabushitake, Hericium erinaceum: bioactive substances and medicinal utilization. Food. Rev. Int. 11, 173-178
Mizuno, T., (1999). The extraction and development of antitumor-active polysaccharides from medicinal mushrooms in Japan (Review). Inter. J. Med. Mushrooms. 1, 9-29.
Musonda, C.A., and Chipman, J.K. (1998). Quercetin inhibits hydrogen peroxide (H2O2)-induced NFkB DNA binding activity and DNA damage in HepG2 cells. Carcinogenesis 19, 1583-9.
Nagata, S. (1999). Fas ligand-induces apoptosis. Annu. Rev. Genet. 33, 29-55.
Oltvai, Z.N., Milliman, C.L. and Korsmeyer, S.J. (1993). Bcl-2 heterodimerizes in vivo with a conserved homology, Bax, that accelerates programmed cell death. Cell 74, 609-19.
Ooi, V.E., and Liu, F. (2000). Immunomodulation and anticancer activity of polysaccharide-protein complexes. Curr. Med. Chem. 7, 715-729
Palmeira, C.M., Moren, A.J., Madeira, V.M., and Wallace, K.B. (1996). Continuous monitoring of mitochondrial membrane potential in hepatocyte cell suspensions. J. Pharmacol. Toxicol. Methods 35, pp. 35–43
Pan, G., O’Rourke, K., Chinnaiyan, A.M., Gentz, R., Ebner, R., Ni, J., and Dixit, V. M. 1997. The receptor for the cytotoxic ligand TRAIL. Science 276, 111-113.
Parkin, D.M., Bray, F., Ferlay, J., and Pisani, P. (2001). Estimating the world cancer burden: GLOBOCAN 2000. Int. J. Cancer. 94, 153–156.
Pitti, R.M., Masters, S.A., Ruppert, S., Donahue, C.J., Morre, A., and Ashkenazi, A. (1996). Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J. Biol. Chem.271, 12687-12690.
Ruddon, R. W. (1996). Cancer biology. Oxford University Press Inc., New York, pp275-403.
Schulze-Osthoff, K., Ferrari, D., Los, M., Wesselborg, S., and Peter, M.E. (1998). Apoptosis signaling by death receptors. Eur. J. Biochem.254, 439-459.
Shen, Y.C., Chou, C.J., Wang, Y.H., Chen, Y.C., and Lu, M.K., (2004). Anti-inflammatory activity of the extracts from mycelia of Antrodia camphorata cultured with water-soluble fractions from five different Cinnamomum species. FEMS Microbiol Lett. 231,137-43.
Sheridan, J.+ P., Marters, S.A., Pitti, P.M., Gurney, A., Skubatch, M., Wood, W. I., Gioddard, P. Ashkenazi, A Baldwin, D., Ramakrishnan, L., Gray, C.L., K., Baker, K. (1997). Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 277, 818-821.
Smith C.A., Farrah T. and Goodwin, R.G. (1994).The TNF receptor superfamily of cellular and viral proteins:activation, costimulation, and death. Cell 76, 959–962
Sone, Y., Okuda, R., Wada, N., Kishida, E. and Misaki, A. (1985). Structures and antitumor activaties of the polysaccharides isolated from fruiting body and the growing culture of mycelium of Ganoderma lucidum. Agric. Biol. Chem. 49, 2641-2653
Song, T.Y., and Yen, G.C. (2002). Antioxidant properties of Antrodia camphorate in submerged culture. J. Agric. Food Chem. 50, 3322-3327
Song, T.Y., and Yen, G.C. (2003). Protective effects of fermented filtrate from Antrodia camphorata in submerged culture against CCl4-induced hepatic toxicity in rats. J Agric Food Chem. 51, 1571– 7.
Tartaglia, L. and Goeddel, D. (1992). Two TNF receptors. Immunol. Today 13, 51–153
Thomas N. S. B., (1996). Apoptosis and cell cycle control in cancer. BIOS Scientific Publishers Ltd.UK. ppl-53.
Thompson C.B. (1995). Apoptosis in the pathogenesis and treatment of disease. Science 267, 1456-1462.
Tsai, Z.T. and Liaw, S.L. (1985). The use and the effect of Ganoderma. San Yun Press: Taichung, Taiwan. p.116.
Tsujimoto Y., Cossman J., Jaffe E. and Croce C. M. (1985). Involvement of the Bcl-2 gene in human follicular lymphoma. Science 228, 1440-3.
Walczak H, Miller R.E., Ariail K, et al. (1999) Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med.5, 157-163.
Walczak H., Degli-Esposti M. A. Jphnson R. S. Smolak P. J. Waugh J. Y. Boiani N. Timour M. S. Gerhart M. J. Schooley K. A. Smith C. A. R. G., Goodwin and C. T. Rauch. (1997). TRAIL-R2: A novel apoptosis-mediating receptor for TRAIL. EMBO J. 16, 5386-5397
Walczak H., Miller R.E, Ariail K., Gliniak B., Griffith T.S., Kubin M., Chin W., Jones J., Woodward A., Le T., Smith C., Smolak P., Goodwin R.G., Rauch C.T., Schuh J.C., and Lynch D.H., (1999). Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat. Med. 5, 157–163
Wang G., Zhang J., Mizuno T., Zhuang C., Ito H., Mayuzumi H., Okamoto H. and Li, J. (1993). Antitumor active polysaccharides from the Chinese mushroom Songshan Lingzhi, the fruiting body of Ganoderma tsugae. Biosci. Biotech.. Biochem. 57, 894-900.
Wang S. Y., Hs, M. L., Hsu H. C., Tzeng C. H., Lee S. S., Shiao M. S. and Ho C. K. (1997). The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages. Int. J. Cancer 70, 699-705.
Wang X. (2001). The expanding role of mitchondria in apoptosis. Genes Dev. 15, 2922-2933
Wasser S.P. (2002). Medicinal mushrooms as a source of anticancer and immunomodulating polysaccharides. Appl Microbiol Biotechnol. 60, 258-274
Wasser, S.P., and Weis, A.L., (1999). Medicinal properties of substances occurring in higher basidomycetes mushrooms: current perspectives (review). Intern. J. Med Mushrooms. 1, 31-62
Wiley, S.R., Schooley, K., Smolak, P.J., Din, W.S., Huang, C.P., Nicholl, J.K., Sutherland, G.R., Smith, T.D., Rauch, C., and Smith, C.A. (1995) Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3, 673-682.
Wu, S.H., Leif, R., and Chang, T.T. (1997) Antrodia camphorata(“niu-chang-chih”), new combination of a medicinal fungus in Taiwan. Bot. Bull. Acad. Sin. 38, 56-64
Yoon, J.H. and Gores, G.J. (2002). Death receptor-mediated apoptosis and the liver. J. Hepatology 37, 400-410.
Yusuf, C. (1999). Solid substrate fermentation, Enzyme production, Food enrichment. Encyclopedia of Bioprocess Technology. Fermentation , Biocatalysis and Bioseparation. 5, 2450-2451.
Zang, M., and Su C.H., (1990). Ganoderma camphoratum, a new taxon in genus Ganoderma from Taiwan. China Acat Bot. Yunnancia. 12, 395-396