中文摘要
目的：本研究旨在探討補充樟芝萃取液對網球衰竭運動後抗疲勞及抗氧化能
力之影響。方法：以12 名大專健康男子乙組選手為研究對象(年齡22.3±1.9 歲；
身高175±7.3 公分；體重71.7±10.3 公斤)，採雙盲交叉實驗設計，每位受試者皆需進行下列四組測試：補充安慰劑無運動組(PR)、補充安慰劑運動組(PE)、補充
樟芝無運動組(AR)、補充樟芝運動組(AE)。樟芝萃取液補充量為每天依受試者體
重每公斤0.1 毫克，為期七天。每位受試者配戴無線式K4B2 代謝系統，在網球
場上以12、15、18、21 球/分鐘對發球機擊球測試最大耗氧量，然後以80％V
O2max之發球速度進行網球落地擊球，直至衰竭為止。運動前、衰竭運動後立即、後30分鐘、後1 小時和後24 小時進行靜脈採血。採二因子共變數分析來考驗補充樟
芝與網球衰竭運動後對血液中血糖、乳酸、肌酸激酶、血氨、丙二醛、過氧化物
歧化酶、榖胱甘肽過氧化酶活性之影響。結果：補充樟芝運動組(AE)的血糖含量
和過氧化物歧化酶活性顯著高於補充安慰劑運動組(PE)(p＜.05)，以及乳酸含量顯
著下降(p＜.05)；然而PE 組與AE 組在肌酸激酶、血氨、丙二醛和榖胱甘肽過氧
化酶活性則無顯著差異(p＞.05)。結論：補充樟芝能有效維持血糖恆定，及快速
有效的代謝乳酸，因此有助於減緩因衰竭運動導致之疲勞；另外，補充樟芝能有
效誘發衰竭運動後過氧化物歧化酶之活性，有助於增強體內抗氧化能力之趨勢，
減緩因衰竭運動導致之氧化傷害。

Abstract
Purpose: The purpose of this study was to investigate the effects of Antroquinonol
supplementation on fatigue and antioxidant activity after exhaustive tennis ground stroke.
Methods: Twelve university tennis club male health subjects participated in the study. The
age, height, body mass of the subjects were 22.3±1.9 yrs, 175±7.3 cm, 71.7 ±10.3 kg
respectively. Double blind cross over design was performed. All subjects had accepted all four
kinds of treatments: (1) placebo without exercise, PR. (2) placebo with exercise, PE. (3)
Antroquinonol supplementation without exercise, AR. (4) Antroquinonol supplementation
with exercise, AE. The amount of Antroquinonol supplementation was 0.1mg per kg of body
weight every day for one week. Subjects’ maximum oxygen uptake was determined by
portable metabolic system (K4B2) hitting the ball frequency of 12, 15, 18, 21 balls/min on the
tennis court. All subjects performed 80% V
O2max intensity of continuous ground stroke
against tennis ball machine until exhaustion. Blood samples were intravenously collected
from the subjects before and after (immediately, 30 min, 1 hr, 24 hr, respectively) the
exhaustive exercise. Two-factor ANCOVA was performed to examine the effects of
exhaustive exercise and Antroquinonol supplementation on glucose(AC), lactate(Lac),
creatine kinase(CK), ammonia(NH3), malondialdehyde (MDA), superoxide dismutase (SOD)
and glutathione peroxidase (GPx) activities. Results: the level of AC, SOD in AE group were
significantly higher (p<.05) than PE group, while the level of Lac in AE group were
significantly lower (p<.05) than PE group. In addition, the level of CK, ammonia, MDA, GPx
were not significantly different (p＞.05) in both two groups. Conclusions: the findings of the
present study showed that Antroquinonol supplementation can effectively maintain blood
glucose constant, fast and efficient metabolism of lactic acid, thereby helping to slow down
due to exhaustive exercise causes fatigue; In addition, the Antroquinonol supplementation
could effectively maintain glucose homeostasis and decrease Lac after exhaustive exercise
and could beneficially reduce exercised-induced fatigue. Moreover, the Antroquinonol
supplementation was beneficial to increase antioxidant status and reduce the elevation of
oxidative stress.

目 次
第壹章 緒論…………………………………………………………………1
第一節 問題背景………………………………………………………1
第二節 研究目的………………………………………………………3
第三節 研究假設………………………………………………………3
第四節 名詞操作性定義………………………………………………4
第五節 研究範圍與限制………………………………………………6
第六節 研究的重要性…………………………………………………7
第貳章 文獻探討……………………………………………………………8
第一節 網球運動………………………………………………………8
第二節 運動與疲勞……………………………………………………9
第三節 運動與抗氧化能力……………………………………………14
第四節 樟芝的簡介與相關文獻………………………………………28
第五節 本章小結………………………………………………………32
第參章 研究方法與步驟…………………………………………………33
第一節 研究對象………………………………………………………33
第二節 材料與儀器……………………………………………………33
第三節 實驗設計………………………………………………………35
第四節 實驗流程………………………………………………………40
第五節 資料處理……………………………………………………44
第肆章 結果………………………………………………………………45
第一節 樟芝補充對網球衰竭運動後抗疲勞能力之影響…………45
第二節 樟芝補充對網球衰竭運動後氧化傷害及抗氧化能力影響…50
第伍章 討論…………………………………………………………………53
第一節 樟芝補充對網球衰竭運動後抗疲勞能力之影響……………53
第二節 樟芝補充對網球衰竭運動後氧化傷害及抗氧化能力影響…57
第陸章 結論與建議…………………………………………………………60
參考文獻………………………………………………………………………61
中文部分…………………………………………………………………61
西文部分…………………………………………………………………64

表 次
表2-4-1 樟芝相關文獻整理……………………………………………………29
表3-3-1 Bruce 法修正之運動負荷表…………………………………………35
表3-3-2 運動自覺量表………………………………………………………36
表3-3-3 實驗施測時間表……………………………………………………39
表4-1-1 受試者基本資料……………………………………………………45
表4-1-2 各組各時間點血糖濃度統計摘要表…………………………………46
表4-1-3 各組各時間點乳酸濃度統計摘要表…………………………………47
表4-1-4 各組各時間點血氨濃度統計摘要表…………………………………48
表4-1-5 各組各時間點肌酸激酶活性統計摘要表……………………………49
表4-2-1 各組各時間點丙二醛濃度統計摘要表………………………………50
表4-2-2 各組各時間點過氧化物歧化酶活性統計摘要表……………………51
表4-2-3 各組各時間點榖胱甘肽過氧化酶活性統計摘要表…………………52

圖 次
圖2-3-1 黃嘌呤氧化酶使ROS 活化之途徑……………………………………18
圖3-2-1 無線式k4b2 配戴圖…………………………………………………34
圖3-2-2 心跳偵測帶和心跳偵測錶……………………………………………34
圖3-3-1 實驗設計圖…………………………………………………………38
圖3-3-2 場地配置圖…………………………………………………………38
圖3-4-1 網球衰竭運動實驗流程圖……………………………………………41

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