Allen, W.E., Jones, G.E., Pollard, J.W., Ridley, A.J., 1997. Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages. J Cell Sci 110 ( Pt 6), 707-720.
Andreasen, P.A., Kjoller, L., Christensen, L., Duffy, M.J., 1997. The urokinase-type plasminogen activator system in cancer metastasis: a review. Int J Cancer 72, 1-22.
Arenberg, D.A., Kunkel, S.L., Polverini, P.J., Glass, M., Burdick, M.D., Strieter, R.M., 1996. Inhibition of interleukin-8 reduces tumorigenesis of human non-small cell lung cancer in SCID mice. J Clin Invest 97, 2792-2802.
Banyard, J., Anand-Apte, B., Symons, M., Zetter, B.R., 2000. Motility and invasion are differentially modulated by Rho family GTPases. Oncogene 19, 580-591.
Berry, K.K., Varney, M.L., Dave, B.J., Bucana, C.D., Fidler, I.J., Singh, R.K., 2001. Expression of interleukin-8 in human metastatic endometrial carcinoma cells and its regulation by inflammatory cytokines. Int J Gynecol Cancer 11, 54-60.
Bloomston, M., Shafii, A., Zervos, E.E., Rosemurgy, A.S., 2002. TIMP-1 overexpression in pancreatic cancer attenuates tumor growth, decreases implantation and metastasis, and inhibits angiogenesis. J Surg Res 102, 39-44.
Borchers, A.T., Keen, C.L., Gershwin, M.E., 2004. Mushrooms, tumors, and immunity: an update. Experimental biology and medicine 229, 393-406.
Boulay, J.-L., O'Shea, J.J., Paul, W.E., 2003. Molecular phylogeny within type I cytokines and their cognate receptors. Immunity 19, 159-163.
Boureux, A., Vignal, E., Faure, S., Fort, P., 2007. Evolution of the Rho family of ras-like GTPases in eukaryotes. Mol Biol Evol 24, 203-216.
Brooks, P.C., Montgomery, A.M., Rosenfeld, M., Reisfeld, R.A., Hu, T., Klier, G., Cheresh, D.A., 1994. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79, 1157-1164.
Brooks, P.C., Stromblad, S., Klemke, R., Visscher, D., Sarkar, F.H., Cheresh, D.A., 1995. Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin. J Clin Invest 96, 1815-1822.
Chadwick, S., Kriegel, C., Amiji, M., 2010. Nanotechnology solutions for mucosal immunization. Adv Drug Deliv Rev 62, 394-407.
Chang, T.-T., Chou, W.-N., 2004. Antrodia cinnamomea reconsidered and A. salmonea sp. nov. on Cunninghamia konishii in Taiwan. Botanical Bulletin of Academia Sinica 45.
Chen, C.C., Liu, Y.W., Ker, Y.B., Wu, Y.Y., Lai, E.Y., Chyau, C.C., Hseu, T.H., Peng, R.Y., 2007. Chemical characterization and anti-inflammatory effect of polysaccharides fractionated from submerge-cultured Antrodia camphorata mycelia. J Agric Food Chem 55, 5007-5012.
Chen, Y.Y., Chou, P.Y., Chien, Y.C., Wu, C.H., Wu, T.S., Sheu, M.J., 2012a. Ethanol extracts of fruiting bodies of Antrodia cinnamomea exhibit anti-migration action in human adenocarcinoma CL1-0 cells through the MAPK and PI3K/AKT signaling pathways. Phytomedicine 19, 768-778.
Chen, Y.Y., Liu, F.C., Chou, P.Y., Chien, Y.C., Chang, W.S., Huang, G.J., Wu, C.H., Sheu, M.J., 2012b. Ethanol Extracts of Fruiting Bodies of Antrodia cinnamomea Suppress CL1-5 Human Lung Adenocarcinoma Cells Migration by Inhibiting Matrix Metalloproteinase-2/9 through ERK, JNK, p38, and PI3K/Akt Signaling Pathways. Evid Based Complement Alternat Med 2012, 378415.
Cheng, J.-J., Yang, C.-J., Cheng, C.-H., Wang, Y.-T., Huang, N.-K., Lu, M.-K., 2005a. Characterization and functional study of Antrodia camphorata lipopolysaccharide. Journal of Agricultural and Food Chemistry 53, 469-474.
Cheng, J.J., Huang, N.K., Chang, T.T., Wang, D.L., Lu, M.K., 2005b. Study for anti-angiogenic activities of polysaccharides isolated from Antrodia cinnamomea in endothelial cells. Life Sci 76, 3029-3042.
Chien, S.C., Chen, M.L., Kuo, H.T., Tsai, Y.C., Lin, B.F., Kuo, Y.H., 2008. Anti-inflammatory activities of new succinic and maleic derivatives from the fruiting body of Antrodia camphorata. J Agric Food Chem 56, 7017-7022.
Clark, A.R., Dean, J.L., The p38 MAPK Pathway in Rheumatoid Arthritis: A Sideways Look. Open Rheumatol J 6, 209-219.
Comalada, M., Xaus, J., Valledor, A.F., Lopez-Lopez, C., Pennington, D.J., Celada, A., 2003. PKC epsilon is involved in JNK activation that mediates LPS-induced TNF-alpha, which induces apoptosis in macrophages. Am J Physiol Cell Physiol 285, C1235-1245.
Dalgleish, A.G., O'Byrne, K.J., 2002. Chronic immune activation and inflammation in the pathogenesis of AIDS and cancer. Advances in cancer research 84, 231-276.
Duggan, C., Maguire, T., McDermott, E., O'Higgins, N., Fennelly, J.J., Duffy, M.J., 1995. Urokinase plasminogen activator and urokinase plasminogen activator receptor in breast cancer. Int J Cancer 61, 597-600.
Felding-Habermann, B., 2003. Integrin adhesion receptors in tumor metastasis. Clin Exp Metastasis 20, 203-213.
Fong, Y.C., Hsu, S.F., Wu, C.L., Li, T.M., Kao, S.T., Tsai, F.J., Chen, W.C., Liu, S.C., Wu, C.M., Tang, C.H., 2009. Transforming growth factor-beta1 increases cell migration and beta1 integrin up-regulation in human lung cancer cells. Lung Cancer 64, 13-21.
Frisch, S.M., Vuori, K., Ruoslahti, E., Chan-Hui, P.Y., 1996. Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol 134, 793-799.
Gandhi, L., Johnson, B.E., 2006. Paraneoplastic syndromes associated with small cell lung cancer. J Natl Compr Canc Netw 4, 631-638.
Geethangili, M., Tzeng, Y.M., 2011. Review of Pharmacological Effects of Antrodia camphorata and Its Bioactive Compounds. Evid Based Complement Alternat Med 2011, 212641.
Gillory, L.A., Stewart, J.E., Megison, M.L., Nabers, H.C., Mroczek-Musulman, E., Beierle, E.A., FAK Inhibition Decreases Hepatoblastoma Survival Both In Vitro and In Vivo. Transl Oncol 6, 206-215.
Gilmore, A.P., Romer, L.H., 1996. Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation. Mol Biol Cell 7, 1209-1224.
Gonzalo, S., Grasa, L., Arruebo, M.P., Plaza, M.A., Murillo, M.D., 2010. Extracellular signal-regulated kinase (ERK) is involved in LPS-induced disturbances in intestinal motility. Neurogastroenterol Motil 23, e80-90.
Greenlee, K.J., Werb, Z., Kheradmand, F., 2007. Matrix metalloproteinases in lung: multiple, multifarious, and multifaceted. Physiol Rev 87, 69-98.
Grise, F., Bidaud, A., Moreau, V., 2009. Rho GTPases in hepatocellular carcinoma. Biochim Biophys Acta 1795, 137-151.
Guo, W., Giancotti, F.G., 2004. Integrin signalling during tumour progression. Nat Rev Mol Cell Biol 5, 816-826.
Han, X., Zhang, H., Jia, M., Han, G., Jiang, W., 2004. Expression of TIMP-3 gene by construction of a eukaryotic cell expression vector and its role in reduction of metastasis in a human breast cancer cell line. Cell Mol Immunol 1, 308-310.
Har-Noy, M., Or, R., 2009. A New Strategy for Immunotherapy of Cancer. Oncology News 4, 110-113.
He, X., Li, X., Liu, B., Xu, L., Zhao, H., Lu, A., 2011. Down-regulation of Treg cells and up-regulation of TH1/TH2 cytokine ratio were induced by polysaccharide from Radix Glycyrrhizae in H22 hepatocarcinoma bearing mice. Molecules 16, 8343-8352.
Hofer, M., Pospisill, M., 1997. Glucan as stimulator of hematopoiesis in normal and gamma-irradiated mice. A survey of the authors' results. International journal of immunopharmacology 19, 607-609.
Hofmann, R., Lehmer, A., Buresch, M., Hartung, R., Ulm, K., 1996. Clinical relevance of urokinase plasminogen activator, its receptor, and its inhibitor in patients with renal cell carcinoma. Cancer 78, 487-492.
Hofmann, U.B., Eggert, A.A., Blass, K., Brocker, E.B., Becker, J.C., 2003. Expression of matrix metalloproteinases in the microenvironment of spontaneous and experimental melanoma metastases reflects the requirements for tumor formation. Cancer Res 63, 8221-8225.
Hseu, Y.-C., Wu, F.-Y., Wu, J.-J., Chen, J.-Y., Chang, W.-H., Lu, F.-J., Lai, Y.-C., Yang, H.-L., 2005. Anti-inflammatory potential of Antrodia Camphorata through inhibition of iNOS, COX-2 and cytokines via the NF-κB pathway. International immunopharmacology 5, 1914-1925.
Hseu, Y.C., Chen, S.C., Yech, Y.J., Wang, L., Yang, H.L., 2008. Antioxidant activity of Antrodia camphorata on free radical-induced endothelial cell damage. J Ethnopharmacol 118, 237-245.
Hseu, Y.C., Yang, H.L., Lai, Y.C., Lin, J.G., Chen, G.W., Chang, Y.H., 2004. Induction of apoptosis by Antrodia camphorata in human premyelocytic leukemia HL-60 cells. Nutr Cancer 48, 189-197.
Hsiao, G., Shen, M.Y., Lin, K.H., Lan, M.H., Wu, L.Y., Chou, D.S., Lin, C.H., Su, C.H., Sheu, J.R., 2003. Antioxidative and hepatoprotective effects of Antrodia camphorata extract. J Agric Food Chem 51, 3302-3308.
Hsieh, Y.H., Chu, F.H., Wang, Y.S., Chien, S.C., Chang, S.T., Shaw, J.F., Chen, C.Y., Hsiao, W.W., Kuo, Y.H., Wang, S.Y., 2010. Antrocamphin A, an anti-inflammatory principal from the fruiting body of Taiwanofungus camphoratus , and its mechanisms. J Agric Food Chem 58, 3153-3158.
Hsu, S.M., Hsu, P.L., 1994. Autocrine and paracrine functions of cytokines in malignant lymphomas. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 48, 433-444.
Hsu, Y.L., Kuo, P.L., Cho, C.Y., Ni, W.C., Tzeng, T.F., Ng, L.T., Kuo, Y.H., Lin, C.C., 2007. Antrodia cinnamomea fruiting bodies extract suppresses the invasive potential of human liver cancer cell line PLC/PRF/5 through inhibition of nuclear factor kappaB pathway. Food Chem Toxicol 45, 1249-1257.
Hsu, Y.L., Kuo, Y.C., Kuo, P.L., Ng, L.T., Kuo, Y.H., Lin, C.C., 2005. Apoptotic effects of extract from Antrodia camphorata fruiting bodies in human hepatocellular carcinoma cell lines. Cancer Lett 221, 77-89.
Huang, C.H., Chang, Y.Y., Liu, C.W., Kang, W.Y., Lin, Y.L., Chang, H.C., Chen, Y.C., 2010. Fruiting body of Niuchangchih (Antrodia camphorata) protects livers against chronic alcohol consumption damage. J Agric Food Chem 58, 3859-3866.
Huang, C.S., Liao, J.W., Hu, M.L., 2008. Lycopene inhibits experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice. J Nutr 138, 538-543.
Hynes, R.O., 2002. Integrins: bidirectional, allosteric signaling machines. Cell 110, 673-687.
Janusz, M.J., Austen, K.F., Czop, J.K., 1989. Isolation of a yeast heptaglucoside that inhibits monocyte phagocytosis of zymosan particles. J Immunol 142, 959-965.
Jason, J., Archibald, L.K., Nwanyanwu, O.C., Byrd, M.G., Kazembe, P.N., Dobbie, H., Jarvis, W.R., 2001. Comparison of serum and cell-specific cytokines in humans.
Clinical and diagnostic laboratory immunology 8, 1097-1103.
Jemal, A., Murray, T., Ward, E., Samuels, A., Tiwari, R.C., Ghafoor, A., Feuer, E.J., Thun, M.J., 2005. Cancer statistics, 2005. CA Cancer J Clin 55, 10-30.
Jimenez-Medina, E., Berruguilla, E., Romero, I., Algarra, I., Collado, A., Garrido, F., Garcia-Lora, A., 2008. The immunomodulator PSK induces in vitro cytotoxic activity in tumour cell lines via arrest of cell cycle and induction of apoptosis. BMC Cancer 8, 78.
Johnson, J.L., Pillai, S., Chellappan, S.P., 2012. Genetic and biochemical alterations in non-small cell lung cancer. Biochem Res Int 2012, 940405.
Kato, H., Liao, Z., Mitsios, J.V., Wang, H.Y., Deryugina, E.I., Varner, J.A., Quigley, J.P., Shattil, S.J., 2012. The primacy of beta1 integrin activation in the metastatic cascade. PLoS One 7, e46576.
Kim, G.Y., Oh, W.K., Shin, B.C., Shin, Y.I., Park, Y.C., Ahn, S.C., Lee, J.D., Bae, Y.S., Kwak, J.Y., Park, Y.M., 2004. Proteoglycan isolated from Phellinus linteus inhibits tumor growth through mechanisms leading to an activation of CD11c+CD8+ DC and type I helper T cell-dominant immune state. FEBS Lett 576, 391-400.
Lacombe, M.L., Milon, L., Munier, A., Mehus, J.G., Lambeth, D.O., 2000. The human Nm23/nucleoside diphosphate kinases. J Bioenerg Biomembr 32, 247-258.
Laidler, P., Gil, D., Pituch-Noworolska, A., Ciolczyk, D., Ksiazek, D., Przybylo, M., Litynska, A., 2000. Expression of beta1-integrins and N-cadherin in bladder cancer and melanoma cell lines. Acta Biochim Pol 47, 1159-1170.
Lee, I.H., Huang, R.L., Chen, C.T., Chen, H.C., Hsu, W.C., Lu, M.K., 2002. Antrodia camphorata polysaccharides exhibit anti-hepatitis B virus effects. FEMS Microbiol Lett 209, 63-67.
Leone, A., Flatow, U., VanHoutte, K., Steeg, P.S., 1993. Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity. Oncogene 8, 2325-2333.
Liabakk, N.B., Talbot, I., Smith, R.A., Wilkinson, K., Balkwill, F., 1996. Matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer. Cancer Res 56, 190-196.
Lieu, C.-W., Lee, S.-S., Wang, S.-Y., 1992. The effect of Ganoderma lucidum on induction of differentiation in leukemic U937 cells. Anticancer research 12, 1211-1215.
Lin, Y.W., Chiang, B.H., 2011. 4-acetylantroquinonol B isolated from Antrodia cinnamomea arrests proliferation of human hepatocellular carcinoma HepG2 cell by affecting p53, p21 and p27 levels. J Agric Food Chem 59, 8625-8631.
Liu, J.J., Huang, T.S., Hsu, M.L., Chen, C.C., Lin, W.S., Lu, F.J., Chang, W.H., 2004. Antitumor effects of the partially purified polysaccharides from Antrodia camphorata and the mechanism of its action. Toxicol Appl Pharmacol 201, 186-193.
Lozano, E., Betson, M., Braga, V.M., 2003. Tumor progression: Small GTPases and loss of cell-cell adhesion. Bioessays 25, 452-463.
Lu, M.C., Du, Y.C., Chuu, J.J., Hwang, S.L., Hsieh, P.C., Hung, C.S., Chang, F.R., Wu, Y.C., 2009. Active extracts of wild fruiting bodies of Antrodia camphorata (EEAC) induce leukemia HL 60 cells apoptosis partially through histone hypoacetylation and synergistically promote anticancer effect of trichostatin A. Arch Toxicol 83, 121-129.
Mehlen, P., Puisieux, A., 2006. Metastasis: a question of life or death. Nat Rev Cancer 6, 449-458.
Meng, X.N., Jin, Y., Yu, Y., Bai, J., Liu, G.Y., Zhu, J., Zhao, Y.Z., Wang, Z., Chen, F., Lee, K.Y., Fu, S.B., 2009. Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion. British Journal of Cancer 101, 327-334.
Miranti, C.K., Brugge, J.S., 2002. Sensing the environment: a historical perspective on integrin signal transduction. Nat Cell Biol 4, E83-90.
Mizel, S.B., Farrar, J.J., 1979. Revised nomenclature for antigen-nonspecific T-cell proliferation and helper factors. Cellular immunology 48, 433-436.
Monteseirin, J., Chacon, P., Vega, A., El Bekay, R., Alvarez, M., Alba, G., Conde, M., Jimenez, J., Asturias, J.A., Martinez, A., Conde, J., Pintado, E., Bedoya, F.J., Sobrino, F., 2004. Human neutrophils synthesize IL-8 in an IgE-mediated activation. J Leukoc Biol 76, 692-700.
Morla, A.O., Mogford, J.E., 2000. Control of smooth muscle cell proliferation and phenotype by integrin signaling through focal adhesion kinase. Biochem Biophys Res Commun 272, 298-302.
Murakami, M., Meneses, P.I., Lan, K., Robertson, E.S., 2008. The suppressor of metastasis Nm23-H1 interacts with the Cdc42 Rho family member and the pleckstrin homology domain of oncoprotein Dbl-1 to suppress cell migration. Cancer biology & therapy 7, 677-688.
Nakayama, T., Ohtsuru, A., Nakao, K., Shima, M., Nakata, K., Watanabe, K., Ishii, N., Kimura, N., Nagataki, S., 1992. Expression in human hepatocellular carcinoma of nucleoside diphosphate kinase, a homologue of the nm23 gene product. J Natl Cancer Inst 84, 1349-1354.
Nikolopoulos, S.N., Blaikie, P., Yoshioka, T., Guo, W., Giancotti, F.G., 2004. Integrin beta4 signaling promotes tumor angiogenesis. Cancer Cell 6, 471-483.
Okada, A., 1999. Roles of matrix metalloproteinases and tissue inhibitor of metalloproteinase (TIMP) in cancer invasion and metastasis. Gan to kagaku ryoho. Cancer & chemotherapy 26, 2247-2252.
Parmo-Cabanas, M., Molina-Ortiz, I., Matias-Roman, S., Garcia-Bernal, D., Carvajal-Vergara, X., Valle, I., Pandiella, A., Arroyo, A.G., Teixido, J., 2006. Role of metalloproteinases MMP-9 and MT1-MMP in CXCL12-promoted myeloma cell invasion across basement membranes. J Pathol 208, 108-118.
Patterson, M.L., Atkinson, S.J., Knauper, V., Murphy, G., 2001. Specific collagenolysis by gelatinase A, MMP-2, is determined by the hemopexin domain and not the fibronectin-like domain. FEBS Lett 503, 158-162.
Pellegrini, P., Berghella, A.M., Del Beato, T., Cicia, S., Adorno, D., Casciani, C.U., 1996. Disregulation in TH1 and TH2 subsets of CD4+ T cells in peripheral blood of colorectal cancer patients and involvement in cancer establishment and progression. Cancer Immunol Immunother 42, 1-8.
Peng, C.C., Chen, K.C., Peng, R.Y., Su, C.H., Hsieh-Li, H.M., 2006. Human urinary bladder cancer T24 cells are susceptible to the Antrodia camphorata extracts. Cancer Lett 243, 109-119.
Rao, Y.K., Wu, A.T., Geethangili, M., Huang, M.T., Chao, W.J., Wu, C.H., Deng, W.P., Yeh, C.T., Tzeng, Y.M., 2010. Identification of antrocin from Antrodia camphorata as a selective and novel class of small molecule inhibitor of Akt/mTOR signaling in metastatic breast cancer MDA-MB-231 cells. Chem Res Toxicol 24, 238-245.
Reddy, K.B., Nabha, S.M., Atanaskova, N., 2003. Role of MAP kinase in tumor progression and invasion. Cancer Metastasis Rev 22, 395-403.
Rosti, G., Bevilacqua, G., Bidoli, P., Portalone, L., Santo, A., Genestreti, G., 2006. Small cell lung cancer. Ann Oncol 17 Suppl 2, ii5-10.
Rundhaug, J.E., 2005. Matrix metalloproteinases and angiogenesis. Journal of cellular and molecular medicine 9, 267-285.
Scesnaite, A., Jarmalaite, S., Mutanen, P., Anttila, S., Nyberg, F., Benhamou, S., Boffetta, P., Husgafvel-Pursiainen, K., 2012. Similar DNA methylation pattern in lung tumours from smokers and never-smokers with second-hand tobacco smoke exposure. Mutagenesis 27, 423-429.
Schaller, M.D., 2010. Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions. J Cell Sci 123, 1007-1013.
Schlaepfer, D.D., Hanks, S.K., Hunter, T., van der Geer, P., 1994. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372, 786-791.
Seetoo, D.Q., Crowe, P.J., Russell, P.J., Yang, J.L., 2003. Quantitative expression of protein markers of plasminogen activation system in prognosis of colorectal cancer. J Surg Oncol 82, 184-193.
Sekine, Y., Tsuji, S., Ikeda, O., Sugiyma, K., Oritani, K., Shimoda, K., Muromoto, R., Ohbayashi, N., Yoshimura, A., Matsuda, T., 2007. Signal-transducing adaptor protein-2 regulates integrin-mediated T cell adhesion through protein degradation of focal adhesion kinase. J Immunol 179, 2397-2407.
Sharma, R.A., Dalgleish, A.G., Steward, W.P., O'Byrne, K.J., 2003. Angiogenesis and the immune response as targets for the prevention and treatment of colorectal cancer (Review). Oncology reports 10, 1625-1631.
Shibata, M., Nezu, T., Kanou, H., Abe, H., Takekawa, M., Fukuzawa, M., 2002. Decreased production of interleukin-12 and type 2 immune responses are marked in cachectic patients with colorectal and gastric cancer. J Clin Gastroenterol 34, 416-420.
Shurin, M.R., Lu, L., Kalinski, P., Stewart-Akers, A.M., Lotze, M.T., 1999. Th1/Th2 balance in cancer, transplantation and pregnancy. Springer seminars in immunopathology 21, 339-359.
Song, T.Y., Hsu, S.L., Yen, G.C., 2005. Induction of apoptosis in human hepatoma cells by mycelia of Antrodia camphorata in submerged culture. J Ethnopharmacol 100, 158-167.
Sood, A.K., Coffin, J.E., Schneider, G.B., Fletcher, M.S., DeYoung, B.R., Gruman, L.M., Gershenson, D.M., Schaller, M.D., Hendrix, M.J., 2004. Biological significance of focal adhesion kinase in ovarian cancer: role in migration and invasion. Am J Pathol 165, 1087-1095.
Steeg, P.S., Bevilacqua, G., Kopper, L., Thorgeirsson, U.P., Talmadge, J.E., Liotta, L.A., Sobel, M.E., 1988. Evidence for a novel gene associated with low tumor metastatic potential. J Natl Cancer Inst 80, 200-204.
Stefansson, S., Lawrence, D.A., 2003. Old dogs and new tricks: proteases, inhibitors, and cell migration. Sci STKE 2003, pe24.
Stefansson, S., Su, E.J., Ishigami, S., Cale, J.M., Gao, Y., Gorlatova, N., Lawrence, D.A., 2007. The contributions of integrin affinity and integrin-cytoskeletal engagement in endothelial and smooth muscle cell adhesion to vitronectin. J Biol Chem 282, 15679-15689.
Stout, R.D., Jiang, C., Matta, B., Tietzel, I., Watkins, S.K., Suttles, J., 2005. Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. The Journal of Immunology 175, 342-349.
Svensson, C., Part, K., Kunnis-Beres, K., Kaldmae, M., Fernaeus, S.Z., Land, T., 2011. Pro-survival effects of JNK and p38 MAPK pathways in LPS-induced activation of BV-2 cells. Biochem Biophys Res Commun 406, 488-492.
Talmadge, J.E., Fidler, I.J., 2010. AACR centennial series: the biology of cancer metastasis: historical perspective. Cancer Res 70, 5649-5669.
Travis, W.D., 2011. Pathology of lung cancer. Clin Chest Med 32, 669-692.
Valavanidis, A., Fiotakis, K., Vlachogianni, T., 2008. Airborne particulate matter and human health: toxicological assessment and importance of size and composition of particles for oxidative damage and carcinogenic mechanisms. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 26, 339-362.
Vaughan, D.E., 2002. PAI-1 and cellular migration: dabbling in paradox. Arterioscler Thromb Vasc Biol 22, 1522-1523.
Visse, R., Nagase, H., 2003. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res 92, 827-839.
Voronov, E., Apte, R., Sofer, S., 1999. The systemic inflammatory response syndrome related to the release of cytokines following severe envenomation. Journal of Venomous Animals and Toxins 5, 5-33.
Weigelt, B., Peterse, J.L., van 't Veer, L.J., 2005. Breast cancer metastasis: markers and models. Nat Rev Cancer 5, 591-602.
Woessner, J.F., Jr., 1991. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J 5, 2145-2154.
Wu, S.H., Ryvarden, L., Chang, T.T., 1997. Antrodia camphorata (“niu-chang-chih”), new combination of a medicinal fungus in Taiwan. Botanical Bulletin of Academia Sinica (Taipei) 38, 273–275.
Yang, C.M., Zhou, Y.J., Wang, R.J., Hu, M.L., 2009. Anti-angiogenic effects and mechanisms of polysaccharides from Antrodia cinnamomea with different molecular weights. J Ethnopharmacol 123, 407-412.
Yang, H.L., Hseu, Y.C., Chen, J.Y., Yech, Y.J., Lu, F.J., Wang, H.H., Lin, P.S., Wang, B.C., 2006. Antrodia camphorata in submerged culture protects low density lipoproteins against oxidative modification. Am J Chin Med 34, 217-231.
Yang, H.L., Kuo, Y.H., Tsai, C.T., Huang, Y.T., Chen, S.C., Chang, H.W., Lin, E., Lin, W.H., Hseu, Y.C., 2011. Anti-metastatic activities of Antrodia camphorata against human breast cancer cells mediated through suppression of the MAPK signaling pathway. Food Chem Toxicol 49, 290-298.
Zang, M., Su, C.H.,, 1990. Ganoderma comphoratum, a new taxon in genus Ganoderma from Taiwan, China. Acta Botanica Yunnanica 12, 395–396.
Zhang, X.H., 2013. Why cancer cells metastasize? Med Hypotheses.
Zhao, S.S., Leung, K.S., 2010. Quality evaluation of mycelial Antrodia camphorata using high-performance liquid chromatography (HPLC) coupled with diode array detector and mass spectrometry (DAD-MS). Chin Med 5, 4.
Zheng, H., Abdel Aziz, H.O., Nakanishi, Y., Masuda, S., Saito, H., Tsuneyama, K., Takano, Y., 2007. Oncogenic role of JC virus in lung cancer. J Pathol 212, 306-315.
Ao, Z.H., Xu, Z.H., Lu, Z.M., Xu, H.Y., Zhang, X.M., Dou, W.F., 2009. Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases. Journal of Ethnopharmacology 121, 194-212.
Birch, M., Mitchell, S., Hart, I.R., 1991. Isolation and characterization of human melanoma cell variants expressing high and low levels of CD44. Cancer Res 51, 6660-6667.
Bloomston, M., Shafii, A., Zervos, E.E., Rosemurgy, A.S., 2002. TIMP-1 overexpression in pancreatic cancer attenuates tumor growth, decreases implantation and metastasis, and inhibits angiogenesis. J Surg Res 102, 39-44.
Boissan, M., De Wever, O., Lizarraga, F., Wendum, D., Poincloux, R., Chignard, N., Desbois-Mouthon, C., Dufour, S., Nawrocki-Raby, B., Birembaut, P., Bracke, M., Chavrier, P., Gespach, C., Lacombe, M.L., Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells. Cancer Res 70, 7710-7722.
Bradford, M., 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
Chadwick, S., Kriegel, C., Amiji, M., 2010. Nanotechnology solutions for mucosal immunization. Adv Drug Deliv Rev 62, 394-407.
Chen, C.C., Liu, Y.W., Ker, Y.B., Wu, Y.Y., Lai, E.Y., Chyau, C.C., Hseu, T.H., Peng, R.Y., 2007. Chemical characterization and anti-inflammatory effect of polysaccharides fractionated from submerge-cultured Antrodia camphorata mycelia. J Agric Food Chem 55, 5007-5012.
Chen, Y.Y., Liu, F.C., Chou, P.Y., Chien, Y.C., Chang, W.S., Huang, G.J., Wu, C.H., Sheu, M.J., 2012. Ethanol Extracts of Fruiting Bodies of Antrodia cinnamomea Suppress CL1-5 Human Lung Adenocarcinoma Cells Migration by Inhibiting Matrix Metalloproteinase-2/9 through ERK, JNK, p38, and PI3K/Akt Signaling Pathways. Evid Based Complement Alternat Med 2012, 378415.
Cheng, J.J., Huang, N.K., Chang, T.T., Wang, D.L., Lu, M.K., 2005. Study for anti-angiogenic activities of polysaccharides isolated from Antrodia cinnamomea in endothelial cells. Life Sci 76, 3029-3042.
Cheng, S., Alfonso-Jaume, M.A., Mertens, P.R., Lovett, D.H., 2002. Tumour metastasis suppressor, nm23-beta, inhibits gelatinase A transcription by interference with transactivator Y-box protein-1 (YB-1). Biochem J 366, 807-816.
Chirco, R., Liu, X.W., Jung, K.K., Kim, H.R., 2006. Novel functions of TIMPs in cell signaling. Cancer Metastasis Rev 25, 99-113.
Fong, Y.C., Hsu, S.F., Wu, C.L., Li, T.M., Kao, S.T., Tsai, F.J., Chen, W.C., Liu, S.C., Wu, C.M., Tang, C.H., 2009. Transforming growth factor-beta1 increases cell
migration and beta1 integrin up-regulation in human lung cancer cells. Lung Cancer 64, 13-21.
Ghoneum, M., Gollapudi, S., 2005. Modified arabinoxylan rice bran (MGN-3/Biobran) enhances yeast-induced apoptosis in human breast cancer cells in vitro. Anticancer Res 25, 859-870.
Han, S.B., Lee, C.W., Kang, J.S., Yoon, Y.D., Lee, K.H., Lee, K., Park, S.K., Kim, H.M., 2006. Acidic polysaccharide from Phellinus linteus inhibits melanoma cell metastasis by blocking cell adhesion and invasion. Int Immunopharmacol 6, 697-702.
Herrera-Gayol, A., Jothy, S., 1999. CD44 modulates Hs578T human breast cancer cell adhesion, migration, and invasiveness. Exp Mol Pathol 66, 99-108.
Hseu, Y.C., Chen, S.C., Yech, Y.J., Wang, L., Yang, H.L., 2008. Antioxidant activity of Antrodia camphorata on free radical-induced endothelial cell damage. J Ethnopharmacol 118, 237-245.
Hseu, Y.C., Yang, H.L., Lai, Y.C., Lin, J.G., Chen, G.W., Chang, Y.H., 2004. Induction of apoptosis by Antrodia camphorata in human premyelocytic leukemia HL-60 cells. Nutr Cancer 48, 189-197.
Hsiao, G., Shen, M.Y., Lin, K.H., Lan, M.H., Wu, L.Y., Chou, D.S., Lin, C.H., Su, C.H., Sheu, J.R., 2003. Antioxidative and hepatoprotective effects of Antrodia camphorata extract. J Agric Food Chem 51, 3302-3308.
Hsieh, Y.H., Chu, F.H., Wang, Y.S., Chien, S.C., Chang, S.T., Shaw, J.F., Chen, C.Y., Hsiao, W.W., Kuo, Y.H., Wang, S.Y., 2010. Antrocamphin A, an anti-inflammatory principal from the fruiting body of Taiwanofungus camphoratus , and its mechanisms. J Agric Food Chem 58, 3153-3158.
Hsu, Y.L., Kuo, P.L., Cho, C.Y., Ni, W.C., Tzeng, T.F., Ng, L.T., Kuo, Y.H., Lin, C.C., 2007. Antrodia cinnamomea fruiting bodies extract suppresses the invasive potential of human liver cancer cell line PLC/PRF/5 through inhibition of nuclear factor kappaB pathway. Food Chem Toxicol 45, 1249-1257.
Hsu, Y.L., Kuo, Y.C., Kuo, P.L., Ng, L.T., Kuo, Y.H., Lin, C.C., 2005. Apoptotic effects of extract from Antrodia camphorata fruiting bodies in human hepatocellular carcinoma cell lines. Cancer Lett 221, 77-89.
Huang, C.H., Chang, Y.Y., Liu, C.W., Kang, W.Y., Lin, Y.L., Chang, H.C., Chen, Y.C., 2010. Fruiting body of Niuchangchih (Antrodia camphorata) protects livers against chronic alcohol consumption damage. J Agric Food Chem 58, 3859-3866.
Hynes, R.O., 2002. Integrins: bidirectional, allosteric signaling machines. Cell 110, 673-687.
Iiizumi, M., Liu, W., Pai, S.K., Furuta, E., Watabe, K., 2008. Drug development against metastasis-related genes and their pathways: a rationale for cancer therapy. Biochim Biophys Acta 1786, 87-104.
Ker, Y.B., Chen, K.C., Chyau, C.C., Chen, C.C., Guo, J.H., Hsieh, C.L., Wang, H.E., Peng, C.C., Chang, C.H., Peng, R.Y., 2005. Antioxidant capability of polysaccharides fractionated from submerge-cultured Agaricus blazei mycelia. J Agric Food Chem 53, 7052-7058.
Kim, Y.M., Kim, I.H., Nam, T.J., 2013. Inhibition of AGS human gastric cancer cell invasion and proliferation by Capsosiphon fulvescens glycoprotein. Mol Med Rep 8, 11-16.
Kleiner, D.E., Stetler-Stevenson, W.G., 1994. Quantitative zymography: detection of picogram quantities of gelatinases. Anal Biochem 218, 325-329.
Kuppers, D.A., Lan, K., Knight, J.S., Robertson, E.S., 2005. Regulation of matrix metalloproteinase 9 expression by Epstein-Barr virus nuclear antigen 3C and the suppressor of metastasis Nm23-H1. J Virol 79, 9714-9724.
Leco, K.J., Apte, S.S., Taniguchi, G.T., Hawkes, S.P., Khokha, R., Schultz, G.A., Edwards, D.R., 1997. Murine tissue inhibitor of metalloproteinases-4 (Timp-4): cDNA isolation and expression in adult mouse tissues. FEBS Lett 401, 213-217.
Lim, S.H., Lee, H.Y., Lee, H.S., 1998. Inhibition of colonization and cell-matrix adhesion after nm23-H1 transfection of human prostate carcinoma cells. Cancer Letters 133, 143-149.
Lim, Y.P., Kuo, S.C., Lai, M.L., Huang, J.D., 2009. Inhibition of CYP3A4 expression by ketoconazole is mediated by the disruption of pregnane X receptor, steroid receptor coactivator-1, and hepatocyte nuclear factor 4alpha interaction. Pharmacogenet Genomics 19, 11-24.
Liu, J.J., Huang, T.S., Hsu, M.L., Chen, C.C., Lin, W.S., Lu, F.J., Chang, W.H., 2004. Antitumor effects of the partially purified polysaccharides from Antrodia camphorata and the mechanism of its action. Toxicol Appl Pharmacol 201, 186-193.
Lozano, E., Betson, M., Braga, V.M., 2003. Tumor progression: Small GTPases and loss of cell-cell adhesion. Bioessays 25, 452-463.
Mackay, A.R., Corbitt, R.H., Hartzler, J.L., Thorgeirsson, U.P., 1990. Basement membrane type IV collagen degradation: evidence for the involvement of a proteolytic cascade independent of metalloproteinases. Cancer Res 50, 5997-6001.
Maehara, Y., Tsujitani, S., Saeki, H., Oki, E., Yoshinaga, K., Emi, Y., Morita, M., Kohnoe, S., Kakeji, Y., Yano, T., Baba, H., 2012. Biological mechanism and clinical effect of protein-bound polysaccharide K (KRESTIN): review of development and future perspectives. Surg Today 42, 8-28.
Miranti, C.K., Brugge, J.S., 2002. Sensing the environment: a historical perspective on integrin signal transduction. Nat Cell Biol 4, E83-90.
Okada, A., 1999. Roles of matrix metalloproteinases and tissue inhibitor of metalloproteinase (TIMP) in cancer invasion and metastasis. Gan to kagaku ryoho. Cancer & chemotherapy 26, 2247-2252.
Repesh, L.A., 1989. A new in vitro assay for quantitating tumor cell invasion. Invasion Metastasis 9, 192-208.
Russell, R.L., Pedersen, A.N., Kantor, J., Geisinger, K., Long, R., Zbieranski, N., Townsend, A., Shelton, B., Brunner, N., Kute, T.E., 1998. Relationship of nm23 to proteolytic factors, proliferation and motility in breast cancer tissues and cell lines. Br J Cancer 78, 710-717.
Saleem, S., Li, J., Yee, S.P., Fellows, G.F., Goodyer, C.G., Wang, R., 2009. beta1 integrin/FAK/ERK signalling pathway is essential for human fetal islet cell differentiation and survival. J Pathol 219, 182-192.
Salerno, M., Palmieri, D., Bouadis, A., Halverson, D., Steeg, P.S., 2005. Nm23-H1 metastasis suppressor expression level influences the binding properties, stability, and function of the kinase suppressor of Ras1 (KSR1) Erk scaffold in breast carcinoma cells. Mol Cell Biol 25, 1379-1388.
Scesnaite, A., Jarmalaite, S., Mutanen, P., Anttila, S., Nyberg, F., Benhamou, S., Boffetta, P., Husgafvel-Pursiainen, K., 2012. Similar DNA methylation pattern in lung tumours from smokers and never-smokers with second-hand tobacco smoke exposure. Mutagenesis 27, 423-429.
She, S., Xu, B., He, M., Lan, X., Wang, Q., Nm23-H1 suppresses hepatocarcinoma cell adhesion and migration on fibronectin by modulating glycosylation of integrin beta1. J Exp Clin Cancer Res 29, 93.
Shen, Y., Ma, Y., Gao, M., Lai, Y., Wang, G., Yu, Q., Cui, F.Z., Liu, X., 2013. Integrins-FAK-Rho GTPases Pathway in Endothelial Cells Sense and Response to Surface Wettability of Plasma Nanocoatings. ACS applied materials & interfaces 5, 5112-5121.
Siegel, R., Naishadham, D., Jemal, A., Cancer statistics, 2013. CA: A Cancer Journal for Clinicians 63, 11-30.
Song, K.S., Li, G., Kim, J.S., Jing, K., Kim, T.D., Kim, J.P., Seo, S.B., Yoo, J.K., Park, H.D., Hwang, B.D., Lim, K., Yoon, W.H., 2011. Protein-bound polysaccharide from Phellinus linteus inhibits tumor growth, invasion, and angiogenesis and alters Wnt/beta-catenin in SW480 human colon cancer cells. BMC Cancer 11, 307.
Song, T.Y., Hsu, S.L., Yen, G.C., 2005. Induction of apoptosis in human hepatoma cells by mycelia of Antrodia camphorata in submerged culture. J Ethnopharmacol 100, 158-167.
Stefansson, S., Lawrence, D.A., 2003. Old dogs and new tricks: proteases, inhibitors, and cell migration. Sci STKE 2003, pe24.
Stefansson, S., Su, E.J., Ishigami, S., Cale, J.M., Gao, Y., Gorlatova, N., Lawrence, D.A., 2007. The contributions of integrin affinity and integrin-cytoskeletal engagement in endothelial and smooth muscle cell adhesion to vitronectin. J Biol Chem 282, 15679-15689.
Tokita, Y., Nakajima, K., Mochida, H., Iha, M., Nagamine, T., 2010. Development of a fucoidan-specific antibody and measurement of fucoidan in serum and urine by sandwich ELISA. Biosci Biotechnol Biochem 74, 350-357.
Yang, C.M., Zhou, Y.J., Wang, R.J., Hu, M.L., 2009. Anti-angiogenic effects and mechanisms of polysaccharides from Antrodia cinnamomea with different molecular weights. J Ethnopharmacol 123, 407-412.
Yang, H.L., Hseu, Y.C., Chen, J.Y., Yech, Y.J., Lu, F.J., Wang, H.H., Lin, P.S., Wang, B.C., 2006. Antrodia camphorata in submerged culture protects low density lipoproteins against oxidative modification. Am J Chin Med 34, 217-231.
Yang, H.L., Kuo, Y.H., Tsai, C.T., Huang, Y.T., Chen, S.C., Chang, H.W., Lin, E., Lin, W.H., Hseu, Y.C., 2011. Anti-metastatic activities of Antrodia camphorata against human breast cancer cells mediated through suppression of the MAPK signaling pathway. Food Chem Toxicol 49, 290-298.
張婉琳。2013。樟芝菌絲體醣蛋白之化學與免疫學的特性。弘光科技大學生物科技研究所碩士論文。Ao, Z.H., Xu, Z.H., Lu, Z.M., Xu, H.Y., Zhang, X.M., Dou, W.F., 2009. Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases. Journal of Ethnopharmacology 121, 194-212.
Ara, T., Song, L., Shimada, H., Keshelava, N., Russell, H.V., Metelitsa, L.S., Groshen, microenvironment promotes the growth and survival of neuroblastoma cells. Cancer Res 69, 329-337.
Birch, M., Mitchell, S., Hart, I.R., 1991. Isolation and characterization of human melanoma cell variants expressing high and low levels of CD44. Cancer Res 51, 6660-6667.
Borchers, A.T., Keen, C.L., Gershwin, M.E., 2004. Mushrooms, tumors, and immunity: an update. Experimental biology and medicine 229, 393-406.
Bradford, M., 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
Brown, G.D., Gordon, S., 2003. Fungal beta-glucans and mammalian immunity. Immunity 19, 311-315.
Brunda, M.J., Luistro, L., Warrier, R.R., Wright, R.B., Hubbard, B.R., Murphy, M., Wolf, S.F., Gately, M.K., 1993. Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J Exp Med 178, 1223-1230.
Chadwick, S., Kriegel, C., Amiji, M., 2010. Nanotechnology solutions for mucosal immunization. Adv Drug Deliv Rev 62, 394-407.
Chen, C.C., Liu, Y.W., Ker, Y.B., Wu, Y.Y., Lai, E.Y., Chyau, C.C., Hseu, T.H., Peng, R.Y., 2007. Chemical characterization and anti-inflammatory effect of polysaccharides fractionated from submerge-cultured Antrodia camphorata mycelia. J Agric Food Chem 55, 5007-5012.
Fan, Y., Ye, J., Shen, F., Zhu, Y., Yeghiazarians, Y., Zhu, W., Chen, Y., Lawton, M.T., Young, W.L., Yang, G.Y., 2008. Interleukin-6 stimulates circulating blood-derived endothelial progenitor cell angiogenesis in vitro. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 28, 90-98.
Fukushima, M., 1989. The overdose of drugs in Japan. Nature 342, 850-851.
Gately, M.K., Gubler, U., Brunda, M.J., Nadeau, R.R., Anderson, T.D., Lipman, J.M., Sarmiento, U., 1994. Interleukin-12: a cytokine with therapeutic potential in oncology and infectious diseases. Therapeutic immunology 1, 187-196.
Har-Noy, M., Or, R., 2009. A New Strategy for Immunotherapy of Cancer. Oncology News 4, 110-113.
He, X., Li, X., Liu, B., Xu, L., Zhao, H., Lu, A., 2011. Down-regulation of Treg cells and up-regulation of TH1/TH2 cytokine ratio were induced by polysaccharide from Radix Glycyrrhizae in H22 hepatocarcinoma bearing mice. Molecules 16, 8343-8352.
Herrera-Gayol, A., Jothy, S., 1999. CD44 modulates Hs578T human breast cancer cell adhesion, migration, and invasiveness. Exp Mol Pathol 66, 99-108.
Hsu, H.Y., Hua, K.F., Lin, C.C., Lin, C.H., Hsu, J., Wong, C.H., 2004. Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathways. J Immunol 173, 5989-5999.
Huang, C.S., Liao, J.W., Hu, M.L., 2008. Lycopene inhibits experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice. J Nutr 138, 538-543.
Inoue, K., Slaton, J.W., Eve, B.Y., Kim, S.J., Perrotte, P., Balbay, M.D., Yano, S., Bar-Eli, M., Radinsky, R., Pettaway, C.A., Dinney, C.P., 2000a. Interleukin 8 expression regulates tumorigenicity and metastases in androgen-independent prostate cancer. Clin Cancer Res 6, 2104-2119.
Inoue, K., Slaton, J.W., Kim, S.J., Perrotte, P., Eve, B.Y., Bar-Eli, M., Radinsky, R., Dinney, C.P., 2000b. Interleukin 8 expression regulates tumorigenicity and metastasis in human bladder cancer. Cancer Res 60, 2290-2299.
Karmakar, S., Dhar, R., Das, C., 2004. Inhibition of cytotrophoblastic (JEG-3) cell invasion by interleukin 12 involves an interferon gamma-mediated pathway. J Biol Chem 279, 55297-55307.
Ker, Y.B., Chen, K.C., Chyau, C.C., Chen, C.C., Guo, J.H., Hsieh, C.L., Wang, H.E., Peng, C.C., Chang, C.H., Peng, R.Y., 2005. Antioxidant capability of polysaccharides fractionated from submerge-cultured Agaricus blazei mycelia. J Agric Food Chem 53, 7052-7058.
Kim, G.Y., Oh, W.K., Shin, B.C., Shin, Y.I., Park, Y.C., Ahn, S.C., Lee, J.D., Bae, Y.S., Kwak, J.Y., Park, Y.M., 2004. Proteoglycan isolated from Phellinus linteus inhibits
tumor growth through mechanisms leading to an activation of CD11c+CD8+ DC and type I helper T cell-dominant immune state. FEBS Lett 576, 391-400.
Kim, M.Y., Oskarsson, T., Acharyya, S., Nguyen, D.X., Zhang, X.H., Norton, L., Massague, J., 2009. Tumor self-seeding by circulating cancer cells. Cell 139, 1315-1326.
Kleiner, D.E., Stetler-Stevenson, W.G., 1994. Quantitative zymography: detection of picogram quantities of gelatinases. Anal Biochem 218, 325-329.
Lim, Y.P., Kuo, S.C., Lai, M.L., Huang, J.D., 2009. Inhibition of CYP3A4 expression by ketoconazole is mediated by the disruption of pregnane X receptor, steroid receptor coactivator-1, and hepatocyte nuclear factor 4alpha interaction. Pharmacogenet Genomics 19, 11-24.
Liu, J.J., Huang, T.S., Hsu, M.L., Chen, C.C., Lin, W.S., Lu, F.J., Chang, W.H., 2004. Antitumor effects of the partially purified polysaccharides from Antrodia camphorata and the mechanism of its action. Toxicol Appl Pharmacol 201, 186-193.
Mehlen, P., Puisieux, A., 2006. Metastasis: a question of life or death. Nat Rev Cancer 6, 449-458.
Moradali, M.F., Mostafavi, H., Ghods, S., Hedjaroude, G.A., 2007. Immunomodulating and anticancer agents in the realm of macromycetes fungi (macrofungi). Int Immunopharmacol 7, 701-724.
Ou, H.T., Shieh, C.J., Chen, J.Y., Chang, H.M., 2005. The antiproliferative and differentiating effects of human leukemic U937 cells are mediated by cytokines from activated mononuclear cells by dietary mushrooms. J Agric Food Chem 53, 300-305.
Repesh, L.A., 1989. A new in vitro assay for quantitating tumor cell invasion. Invasion Metastasis 9, 192-208.
Roomi, M.W., Monterrey, J.C., Kalinovsky, T., Rath, M., Niedzwiecki, A., 2010. In vitro modulation of MMP-2 and MMP-9 in human cervical and ovarian cancer cell lines by cytokines, inducers and inhibitors. Oncol Rep 23, 605-614.
Shiau, M.Y., Fan, L.C., Yang, S.C., Tsao, C.H., Lee, H., Cheng, Y.W., Lai, L.C., Chang, Y.H., 2013. Human papillomavirus up-regulates MMP-2 and MMP-9 expression and activity by inducing interleukin-8 in lung adenocarcinomas. PLoS One 8, e54423.
Shibata, M., Nezu, T., Kanou, H., Abe, H., Takekawa, M., Fukuzawa, M., 2002. Decreased production of interleukin-12 and type 2 immune responses are marked in cachectic patients with colorectal and gastric cancer. J Clin Gastroenterol 34, 416-420.
Shurin, M.R., Lu, L., Kalinski, P., Stewart-Akers, A.M., Lotze, M.T., 1999. Th1/Th2 balance in cancer, transplantation and pregnancy. Springer seminars in immunopathology 21, 339-359.
Tokita, Y., Nakajima, K., Mochida, H., Iha, M., Nagamine, T., 2010. Development of a fucoidan-specific antibody and measurement of fucoidan in serum and urine by sandwich ELISA. Biosci Biotechnol Biochem 74, 350-357.
Yang, C.M., Zhou, Y.J., Wang, R.J., Hu, M.L., 2009. Anti-angiogenic effects and mechanisms of polysaccharides from Antrodia cinnamomea with different molecular weights. J Ethnopharmacol 123, 407-412.
Yao, J.S., Zhai, W., Young, W.L., Yang, G.Y., 2006. Interleukin-6 triggers human cerebral endothelial cells proliferation and migration: the role for KDR and MMP-9. Biochem Biophys Res Commun 342, 1396-1404.